Human SOD1/ALS/ALS1 ORF/cDNA clone-Lentivirus particle (NM_000454)

Cat. No.: vGMLP000506

Pre-made Human SOD1/ALS/ALS1 Lentiviral expression plasmid for SOD1 lentivirus packaging, SOD1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

The GM Vector Core (GMVC) specializes in custom lentivirus development and offers a range of lentivirus manufacturing solutions, leveraging state-of-the-art processes. Learn more about our services.

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Go to SOD Cu-Zn/SOD1/ALS products collection>>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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pdf Datasheet

Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLP000506 Human SOD1 Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLP000506
Gene Name SOD1
Accession Number NM_000454
Gene ID 6647
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 465 bp
Gene Alias ALS,ALS1,HEL-S-44,homodimer,hSod1,IPOA,SOD
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCGACGAAGGCCGTGTGCGTGCTGAAGGGCGACGGCCCAGTGCAGGGCATCATCAATTTCGAGCAGAAGGAAAGTAATGGACCAGTGAAGGTGTGGGGAAGCATTAAAGGACTGACTGAAGGCCTGCATGGATTCCATGTTCATGAGTTTGGAGATAATACAGCAGGCTGTACCAGTGCAGGTCCTCACTTTAATCCTCTATCCAGAAAACACGGTGGGCCAAAGGATGAAGAGAGGCATGTTGGAGACTTGGGCAATGTGACTGCTGACAAAGATGGTGTGGCCGATGTGTCTATTGAAGATTCTGTGATCTCACTCTCAGGAGACCATTGCATCATTGGCCGCACACTGGTGGTCCATGAAAAAGCAGATGACTTGGGCAAAGGTGGAAATGAAGAAAGTACAAAGACAGGAAACGCTGGAAGTCGTTTGGCTTGTGGTGTAATTGGGATCGCCCAATAA
ORF Protein Sequence MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T22977-Ab Anti-SODC/ SOD Cu-Zn/ SOD1 monoclonal antibody
    Target Antigen GM-Tg-g-T22977-Ag SOD Cu-Zn/SOD1 VLP (virus-like particle)
    ORF Viral Vector pGMLP000506 Human SOD1 Lentivirus plasmid
    ORF Viral Vector pGMAP000004 Human SOD1 Adenovirus plasmid
    ORF Viral Vector pGMPC004735 Human SOD1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP000506 Human SOD1 Lentivirus particle
    ORF Viral Vector vGMAP000004 Human SOD1 Adenovirus particle


    Target information

    Target ID GM-T22977
    Target Name SOD Cu-Zn
    Gene ID 6647, 20655, 574096, 24786, 101091804, 403559, 281495, 100033855
    Gene Symbol and Synonyms ALS,ALS1,B430204E11Rik,Cu/Zn-SOD,CuZnSOD,HEL-S-44,homodimer,hSod1,Ipo-1,Ipo1,IPOA,SOD,Sod-1,SOD1,SOD1L1,SODC,STAHP
    Uniprot Accession P00441
    Uniprot Entry Name SODC_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Lung Cancer, ALS
    Gene Ensembl ENSG00000142168
    Target Classification Not Available

    The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2020]



    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.