Human BMP10 ORF/cDNA clone-Lentivirus particle (NM_014482)
Cat. No.: vGMLP001458
Pre-made Human BMP10/ Lentiviral expression plasmid for BMP10 lentivirus packaging, BMP10 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
---|---|---|---|
vGMLP001458 | Human BMP10 Lentivirus particle | Pilot Grade | 1.0E+8TU |
5.0E+8TU | |||
1.0E+9TU | |||
Research Grade | 1.0E+8TU | ||
5.0E+8TU | |||
1.0E+9TU | |||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMLP001458 |
Gene Name | BMP10 |
Accession Number | NM_014482 |
Gene ID | 27302 |
Species | Human |
Product Type | Lentivirus particle (overexpression) |
Insert Length | 1275 bp |
Gene Alias | |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
ORF Nucleotide Sequence | ATGGGCTCTCTGGTCCTGACACTGTGCGCTCTTTTCTGCCTGGCAGCTTACTTGGTTTCTGGCAGCCCCATCATGAACCTAGAGCAGTCTCCTCTGGAAGAAGATATGTCCCTCTTTGGTGATGTTTTCTCAGAGCAAGACGGTGTCGACTTTAACACACTGCTCCAGAGCATGAAGGATGAGTTTCTTAAGACACTAAACCTCTCTGACATCCCCACGCAGGATTCAGCCAAGGTGGACCCACCAGAGTACATGTTGGAACTCTACAACAAATTTGCAACAGATCGGACCTCCATGCCCTCTGCCAACATCATTAGGAGTTTCAAGAATGAAGATCTGTTTTCCCAGCCGGTCAGTTTTAATGGGCTCCGAAAATACCCCCTCCTCTTCAATGTGTCCATTCCTCACCATGAAGAGGTCATCATGGCTGAACTTAGGCTATACACACTGGTGCAAAGGGATCGTATGATATACGATGGAGTAGACCGGAAAATTACCATTTTTGAAGTGCTGGAGAGCAAAGGGGATAATGAGGGAGAAAGAAACATGCTGGTCTTGGTGTCTGGGGAGATATATGGAACCAACAGTGAGTGGGAGACTTTTGATGTCACAGATGCCATCAGACGTTGGCAAAAGTCAGGCTCATCCACCCACCAGCTGGAGGTCCACATTGAGAGCAAACACGATGAAGCTGAGGATGCCAGCAGTGGACGGCTAGAAATAGATACCAGTGCCCAGAATAAGCATAACCCTTTGCTCATCGTGTTTTCTGATGACCAAAGCAGTGACAAGGAGAGGAAGGAGGAACTGAATGAAATGATTTCCCATGAGCAACTTCCAGAGCTGGACAACTTGGGCCTGGATAGCTTTTCCAGTGGACCTGGGGAAGAGGCTTTGTTGCAGATGAGATCAAACATCATCTATGACTCCACTGCCCGAATCAGAAGGAACGCCAAAGGAAACTACTGTAAGAGGACCCCGCTCTACATCGACTTCAAGGAGATTGGGTGGGACTCCTGGATCATCGCTCCGCCTGGATACGAAGCCTATGAATGCCGTGGTGTTTGTAACTACCCCCTGGCAGAGCATCTCACACCCACAAAGCATGCAATTATCCAGGCCTTGGTCCACCTCAAGAATTCCCAGAAAGCTTCCAAAGCCTGCTGTGTGCCCACAAAGCTAGAGCCCATCTCCATCCTCTATTTAGACAAAGGCGTCGTCACCTACAAGTTTAAATACGAAGGCATGGCCGTCTCCGAATGTGGCTGTAGATAG |
ORF Protein Sequence | MGSLVLTLCALFCLAAYLVSGSPIMNLEQSPLEEDMSLFGDVFSEQDGVDFNTLLQSMKDEFLKTLNLSDIPTQDSAKVDPPEYMLELYNKFATDRTSMPSANIIRSFKNEDLFSQPVSFNGLRKYPLLFNVSIPHHEEVIMAELRLYTLVQRDRMIYDGVDRKITIFEVLESKGDNEGERNMLVLVSGEIYGTNSEWETFDVTDAIRRWQKSGSSTHQLEVHIESKHDEAEDASSGRLEIDTSAQNKHNPLLIVFSDDQSSDKERKEELNEMISHEQLPELDNLGLDSFSSGPGEEALLQMRSNIIYDSTARIRRNAKGNYCKRTPLYIDFKEIGWDSWIIAPPGYEAYECRGVCNYPLAEHLTPTKHAIIQALVHLKNSQKASKACCVPTKLEPISILYLDKGVVTYKFKYEGMAVSECGCR |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Biosimilar | GMP-Bios-INN-791 | Pre-Made Dalantercept biosimilar, Fusion Protein: Recombinant therapeutic protein targeting BMP10 fused with human IGHG1 Fc (Fragment constant) |
Target Antibody | GM-Tg-g-T19110-Ab | Anti-BMP10 functional antibody |
Target Antigen | GM-Tg-g-T19110-Ag | BMP10 protein |
ORF Viral Vector | pGMLP001458 | Human BMP10 Lentivirus plasmid |
ORF Viral Vector | vGMLP001458 | Human BMP10 Lentivirus particle |
Target information
Target ID | GM-T19110 |
Target Name | BMP10 |
Gene ID | 27302, 12154, 700068, 500245, 111559830, 481408, 538874, 100050890 |
Gene Symbol and Synonyms | b2b2711Clo,BMP10 |
Uniprot Accession | O95393 |
Uniprot Entry Name | BMP10_HUMAN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Therapeutics Target, INN Index |
Disease | Not Available |
Gene Ensembl | ENSG00000163217 |
Target Classification | Not Available |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation. [provided by RefSeq, Aug 2016]
About GMVC
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