SOLIDEX™ CD66b+ Cell Isolation Solution
Introduction of SOLIDEX™ CD66b+ Cell Isolation Solution
CD66b+ cells mainly refer to neutrophils expressing the CD66b antigen, the most abundant type of white blood cells in the human immune system, accounting for approximately 50-70% of peripheral blood leukocytes, and playing a key role in innate immunity.
CD66b, also known as CD67, CGM6, and NCA-95, is a 95–100 kDa glycosylphosphatidylinositol (GPI)-linked protein expressed on neutrophils and eosinophils, but not on basophils or lymphocytes. GeneMedi provides CD66b magnetic beads for positive selection or depletion of CD66b+ cells to meet various research and therapeutic needs.
Isolation method of SOLIDEX™ CD66b+ Cell Isolation Solution
- Positive Selection
- Depletion
Research Applications:
Pure neutrophils are isolated using anti-CD66b magnetic beads for flow cytometry, cell culture, or DNA/RNA extraction for lineage-specific chimeric analysis, studying the functional characteristics of neutrophils in inflammation or infection.
Clinical Applications:
Positive selection isolates CD66b+ monocytes to study their biological functions, confirming their lack of immunomodulatory effects in cancer and demonstrating enhanced pro-inflammatory capabilities, providing a foundation for immunotherapy in infectious diseases.
| Cat.No | Product Name | Products Information |
|---|---|---|
| GM-Tg-hg-MP0250-iso-nanoIMB | Human CD66b Nano-mag Beads (Column-Based) | Details |
| GM-Tg-hg-MP0250-iso-nanoIMB-CF | Human CD66b Nano-mag Beads (Column-Free) | Details |
| GM-Tg-hg-MP0250-iso-rel-kit | Indirect Releasable Human CD66b+ Cell Isolation Kit (Column-Based) | Details |
| GM-Tg-hg-MP0250-iso-rel-kit-CF | Indirect Releasable Human CD66b+ Cell Isolation Kit (Column-Free) | Details |
| GM-Tg-hg-MP0250-iso-kit | Indirect Human CD66b+ Cell Isolation Kit (Column-Based) | Details |
| GM-Tg-hg-MP0250-iso-kit-CF | Indirect Human CD66b+ Cell Isolation Kit (Column-Free) | Details |
Research Applications:
Removal of neutrophils from PBMCs to obtain pure populations of T cells, B cells, or monocytes for downstream experiments or immune cell functional analysis, while also facilitating studies on the suppressive effects of granulocytes on other immune cells.
| Cat.No | Product Name | Products Information |
|---|---|---|
| GM-Tg-hg-MP0250-dep-nanoIMB | Human CD66b+ Cell Depletion Nano-mag Beads (Column-Based) | Details |
| GM-Tg-hg-MP0250-dep-kit | Indirect Human CD66b+ Cell Depletion Kit (Column-Based) | Details |
