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Anti-CLC1B/ CLEC1B/ 1810061I13Rik monoclonal antibody
Anti-CLC1B/ CLEC1B/ 1810061I13Rik antibody for FACS & in-vivo assay
Go to CLEC1B/CLEC1B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0292-Ab-1/ GM-Tg-hg-MP0292-Ab-2 | Anti-Human CLEC1B monoclonal antibody | Human |
| GM-Tg-rg-MP0292-Ab-1/ GM-Tg-rg-MP0292-Ab-2 | Anti-Rat CLEC1B monoclonal antibody | Rat |
| GM-Tg-mg-MP0292-Ab-1/ GM-Tg-mg-MP0292-Ab-2 | Anti-Mouse CLEC1B monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0292-Ab-1/ GM-Tg-cynog-MP0292-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CLEC1B monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0292-Ab-1/ GM-Tg-felg-MP0292-Ab-2 | Anti-Feline CLEC1B monoclonal antibody | Feline |
| GM-Tg-cang-MP0292-Ab-1/ GM-Tg-cang-MP0292-Ab-2 | Anti-Canine CLEC1B monoclonal antibody | Canine |
| GM-Tg-bovg-MP0292-Ab-1/ GM-Tg-bovg-MP0292-Ab-2 | Anti-Bovine CLEC1B monoclonal antibody | Bovine |
| GM-Tg-equg-MP0292-Ab-1/ GM-Tg-equg-MP0292-Ab-2 | Anti-Equine CLEC1B monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0292-Ab-1/ GM-Tg-hg-MP0292-Ab-2; GM-Tg-rg-MP0292-Ab-1/ GM-Tg-rg-MP0292-Ab-2; GM-Tg-mg-MP0292-Ab-1/ GM-Tg-mg-MP0292-Ab-2; GM-Tg-cynog-MP0292-Ab-1/ GM-Tg-cynog-MP0292-Ab-2; GM-Tg-felg-MP0292-Ab-1/ GM-Tg-felg-MP0292-Ab-2; GM-Tg-cang-MP0292-Ab-1/ GM-Tg-cang-MP0292-Ab-2; GM-Tg-bovg-MP0292-Ab-1/ GM-Tg-bovg-MP0292-Ab-2; GM-Tg-equg-MP0292-Ab-1/ GM-Tg-equg-MP0292-Ab-2 |
| Products Name | Anti-CLEC1B monoclonal antibody |
| Format | mab |
| Target Name | CLEC1B |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CLEC1B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species CLC1B/ CLEC1B/ 1810061I13Rik VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMAD000045 | human CLEC1B Adenovirus plasmid |
| ORF Viral Vector | vGMAD000045 | human CLEC1B Adenovirus particle |
| ORF Viral Vector | pGMLPm001909 | mouse Clec1b Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001909 | mouse Clec1b Lentivirus particle |
Target information
| Target ID | GM-MP0292 |
| Target Name | CLEC1B |
| Gene ID | 51266,56760,500336,717404,109491361,784092,100053758 |
| Gene Symbol and Synonyms | 1810061I13Rik,Clec-2,CLEC1B,CLEC2,CLEC2B,PRO1384,QDED721,RGD1563517 |
| Uniprot Accession | Q9P126 |
| Uniprot Entry Name | CLC1B_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000165682 |
| Target Classification | N/A |
The target: CLEC1B, gene name: CLEC1B, also named as 1810061I13Rik, CLEC2, CLEC2B, PRO1384, QDED721. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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