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Anti-GPM6B/ M6B monoclonal antibody
Anti-GPM6B/ M6B antibody for FACS & in-vivo assay
Go to GPM6B/GPM6B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0497-Ab-1/ GM-Tg-hg-MP0497-Ab-2 | Anti-Human GPM6B monoclonal antibody | Human |
| GM-Tg-rg-MP0497-Ab-1/ GM-Tg-rg-MP0497-Ab-2 | Anti-Rat GPM6B monoclonal antibody | Rat |
| GM-Tg-mg-MP0497-Ab-1/ GM-Tg-mg-MP0497-Ab-2 | Anti-Mouse GPM6B monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0497-Ab-1/ GM-Tg-cynog-MP0497-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GPM6B monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0497-Ab-1/ GM-Tg-felg-MP0497-Ab-2 | Anti-Feline GPM6B monoclonal antibody | Feline |
| GM-Tg-cang-MP0497-Ab-1/ GM-Tg-cang-MP0497-Ab-2 | Anti-Canine GPM6B monoclonal antibody | Canine |
| GM-Tg-bovg-MP0497-Ab-1/ GM-Tg-bovg-MP0497-Ab-2 | Anti-Bovine GPM6B monoclonal antibody | Bovine |
| GM-Tg-equg-MP0497-Ab-1/ GM-Tg-equg-MP0497-Ab-2 | Anti-Equine GPM6B monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0497-Ab-1/ GM-Tg-hg-MP0497-Ab-2; GM-Tg-rg-MP0497-Ab-1/ GM-Tg-rg-MP0497-Ab-2; GM-Tg-mg-MP0497-Ab-1/ GM-Tg-mg-MP0497-Ab-2; GM-Tg-cynog-MP0497-Ab-1/ GM-Tg-cynog-MP0497-Ab-2; GM-Tg-felg-MP0497-Ab-1/ GM-Tg-felg-MP0497-Ab-2; GM-Tg-cang-MP0497-Ab-1/ GM-Tg-cang-MP0497-Ab-2; GM-Tg-bovg-MP0497-Ab-1/ GM-Tg-bovg-MP0497-Ab-2; GM-Tg-equg-MP0497-Ab-1/ GM-Tg-equg-MP0497-Ab-2 |
| Products Name | Anti-GPM6B monoclonal antibody |
| Format | mab |
| Target Name | GPM6B |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-GPM6B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species GPM6B/ M6B VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP003241 | human GPM6B Lentivirus particle |
| ORF Viral Vector | pGMLP003241 | human GPM6B Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000741 | mouse Gpm6b Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000741 | mouse Gpm6b Lentivirus particle |
Target information
| Target ID | GM-MP0497 |
| Target Name | GPM6B |
| Gene ID | 2824,14758,192179,711762,480842,101089746,516689,100050640 |
| Gene Symbol and Synonyms | Gpm6,GPM6B,M6B |
| Uniprot Accession | Q13491,Q9JJK1 |
| Uniprot Entry Name | GPM6B_HUMAN,GPM6B_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Ovary Cancer |
| Gene Ensembl | ENSG00000046653 |
| Target Classification | N/A |
The target: GPM6B, gene name: GPM6B, also named as M6B. This gene encodes a membrane glycoprotein that belongs to the proteolipid protein family. Proteolipid protein family members are expressed in most brain regions and are thought to be involved in cellular housekeeping functions such as membrane trafficking and cell-to-cell communication. This protein may also be involved in osteoblast differentiation. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes Y and 22. [provided by RefSeq, Jan 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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