Anti-GP162/ GPR162/ A-2 monoclonal antibody

Anti-GP162/ GPR162/ A-2 antibody for FACS & in-vivo assay

Target products collectionGo to GPR162/GPR162 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0521-Ab-1/ GM-Tg-hg-MP0521-Ab-2Anti-Human GPR162 monoclonal antibodyHuman
GM-Tg-rg-MP0521-Ab-1/ GM-Tg-rg-MP0521-Ab-2Anti-Rat GPR162 monoclonal antibodyRat
GM-Tg-mg-MP0521-Ab-1/ GM-Tg-mg-MP0521-Ab-2Anti-Mouse GPR162 monoclonal antibodyMouse
GM-Tg-cynog-MP0521-Ab-1/ GM-Tg-cynog-MP0521-Ab-2Anti-Cynomolgus/ Rhesus macaque GPR162 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0521-Ab-1/ GM-Tg-felg-MP0521-Ab-2Anti-Feline GPR162 monoclonal antibodyFeline
GM-Tg-cang-MP0521-Ab-1/ GM-Tg-cang-MP0521-Ab-2Anti-Canine GPR162 monoclonal antibodyCanine
GM-Tg-bovg-MP0521-Ab-1/ GM-Tg-bovg-MP0521-Ab-2Anti-Bovine GPR162 monoclonal antibodyBovine
GM-Tg-equg-MP0521-Ab-1/ GM-Tg-equg-MP0521-Ab-2Anti-Equine GPR162 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0521-Ab-1/ GM-Tg-hg-MP0521-Ab-2; GM-Tg-rg-MP0521-Ab-1/ GM-Tg-rg-MP0521-Ab-2;
GM-Tg-mg-MP0521-Ab-1/ GM-Tg-mg-MP0521-Ab-2; GM-Tg-cynog-MP0521-Ab-1/ GM-Tg-cynog-MP0521-Ab-2;
GM-Tg-felg-MP0521-Ab-1/ GM-Tg-felg-MP0521-Ab-2; GM-Tg-cang-MP0521-Ab-1/ GM-Tg-cang-MP0521-Ab-2;
GM-Tg-bovg-MP0521-Ab-1/ GM-Tg-bovg-MP0521-Ab-2; GM-Tg-equg-MP0521-Ab-1/ GM-Tg-equg-MP0521-Ab-2
Products NameAnti-GPR162 monoclonal antibody
Formatmab
Target NameGPR162
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GPR162 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GP162/ GPR162/ A-2 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMAP000236Human GPR162 Adenovirus particle
    ORF Viral VectorpGMAP000236Human GPR162 Adenovirus plasmid


    Target information

    Target IDGM-MP0521
    Target NameGPR162
    Gene ID27239,14788,362436,100428266,486719,101084547,540410,100146294
    Gene Symbol and SynonymsA-2,GPR162,GRCA
    Uniprot AccessionQ16538
    Uniprot Entry NameGP162_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000250510
    Target ClassificationGPCR

    The target: GPR162, gene name: GPR162, also named as A-2, GRCA. This gene was identified upon genomic analysis of a gene-dense region at human chromosome 12p13. It appears to be mainly expressed in the brain; however, its function is not known. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.