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Anti-GLPA/ GYPA/ CD235a monoclonal antibody
Anti-GLPA/ GYPA/ CD235a antibody for FACS & in-vivo assay
Go to GYPA/GYPA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0565-Ab-1/ GM-Tg-hg-MP0565-Ab-2 | Anti-Human GYPA monoclonal antibody | Human |
| GM-Tg-rg-MP0565-Ab-1/ GM-Tg-rg-MP0565-Ab-2 | Anti-Rat GYPA monoclonal antibody | Rat |
| GM-Tg-mg-MP0565-Ab-1/ GM-Tg-mg-MP0565-Ab-2 | Anti-Mouse GYPA monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0565-Ab-1/ GM-Tg-cynog-MP0565-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GYPA monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0565-Ab-1/ GM-Tg-felg-MP0565-Ab-2 | Anti-Feline GYPA monoclonal antibody | Feline |
| GM-Tg-cang-MP0565-Ab-1/ GM-Tg-cang-MP0565-Ab-2 | Anti-Canine GYPA monoclonal antibody | Canine |
| GM-Tg-bovg-MP0565-Ab-1/ GM-Tg-bovg-MP0565-Ab-2 | Anti-Bovine GYPA monoclonal antibody | Bovine |
| GM-Tg-equg-MP0565-Ab-1/ GM-Tg-equg-MP0565-Ab-2 | Anti-Equine GYPA monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0565-Ab-1/ GM-Tg-hg-MP0565-Ab-2; GM-Tg-rg-MP0565-Ab-1/ GM-Tg-rg-MP0565-Ab-2; GM-Tg-mg-MP0565-Ab-1/ GM-Tg-mg-MP0565-Ab-2; GM-Tg-cynog-MP0565-Ab-1/ GM-Tg-cynog-MP0565-Ab-2; GM-Tg-felg-MP0565-Ab-1/ GM-Tg-felg-MP0565-Ab-2; GM-Tg-cang-MP0565-Ab-1/ GM-Tg-cang-MP0565-Ab-2; GM-Tg-bovg-MP0565-Ab-1/ GM-Tg-bovg-MP0565-Ab-2; GM-Tg-equg-MP0565-Ab-1/ GM-Tg-equg-MP0565-Ab-2 |
| Products Name | Anti-GYPA monoclonal antibody |
| Format | mab |
| Target Name | GYPA |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-GYPA benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species GLPA/ GYPA/ CD235a VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP003338 | human GYPA Lentivirus particle |
| ORF Viral Vector | pGMLP003338 | human GYPA Lentivirus plasmid |
| ORF Viral Vector | pGMLPm001559 | mouse Gypa Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001559 | mouse Gypa Lentivirus particle |
Target information
| Target ID | GM-MP0565 |
| Target Name | GYPA |
| Gene ID | 2993,688972,574101,109498956,617836,102150508 |
| Gene Symbol and Synonyms | CD235a,GPA,GPErik,GPSAT,GYPA,HGpMiV,HGpMiXI,HGpSta(C),MN,MNS,PAS-2 |
| Uniprot Accession | P02724 |
| Uniprot Entry Name | GLPA_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000170180 |
| Target Classification | N/A |
The target: GYPA, gene name: GYPA, also named as CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2. Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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