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Anti-GLPE/ GYPE/ GPE monoclonal antibody
Anti-GLPE/ GYPE/ GPE antibody for FACS & in-vivo assay
Go to GYPE/GYPE products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0568-Ab-1/ GM-Tg-hg-MP0568-Ab-2 | Anti-Human GYPE monoclonal antibody | Human |
| GM-Tg-rg-MP0568-Ab-1/ GM-Tg-rg-MP0568-Ab-2 | Anti-Rat GYPE monoclonal antibody | Rat |
| GM-Tg-mg-MP0568-Ab-1/ GM-Tg-mg-MP0568-Ab-2 | Anti-Mouse GYPE monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0568-Ab-1/ GM-Tg-cynog-MP0568-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GYPE monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0568-Ab-1/ GM-Tg-felg-MP0568-Ab-2 | Anti-Feline GYPE monoclonal antibody | Feline |
| GM-Tg-cang-MP0568-Ab-1/ GM-Tg-cang-MP0568-Ab-2 | Anti-Canine GYPE monoclonal antibody | Canine |
| GM-Tg-bovg-MP0568-Ab-1/ GM-Tg-bovg-MP0568-Ab-2 | Anti-Bovine GYPE monoclonal antibody | Bovine |
| GM-Tg-equg-MP0568-Ab-1/ GM-Tg-equg-MP0568-Ab-2 | Anti-Equine GYPE monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0568-Ab-1/ GM-Tg-hg-MP0568-Ab-2; GM-Tg-rg-MP0568-Ab-1/ GM-Tg-rg-MP0568-Ab-2; GM-Tg-mg-MP0568-Ab-1/ GM-Tg-mg-MP0568-Ab-2; GM-Tg-cynog-MP0568-Ab-1/ GM-Tg-cynog-MP0568-Ab-2; GM-Tg-felg-MP0568-Ab-1/ GM-Tg-felg-MP0568-Ab-2; GM-Tg-cang-MP0568-Ab-1/ GM-Tg-cang-MP0568-Ab-2; GM-Tg-bovg-MP0568-Ab-1/ GM-Tg-bovg-MP0568-Ab-2; GM-Tg-equg-MP0568-Ab-1/ GM-Tg-equg-MP0568-Ab-2 |
| Products Name | Anti-GYPE monoclonal antibody |
| Format | mab |
| Target Name | GYPE |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-GYPE benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species GLPE/ GYPE/ GPE VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP004611 | human GYPE Lentivirus particle |
| ORF Viral Vector | pGMLP004611 | human GYPE Lentivirus plasmid |
Target information
| Target ID | GM-MP0568 |
| Target Name | GYPE |
| Gene ID | 2996 |
| Gene Symbol and Synonyms | GPE,GYPA,GYPE,MiIX,MNS |
| Uniprot Accession | P15421 |
| Uniprot Entry Name | GLPE_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000197465 |
| Target Classification | N/A |
The target: GYPE, gene name: GYPE, also named as GPE, GYPA, MNS, MiIX. The protein encoded by this gene is a sialoglycoprotein and a type I membrane protein. It is a member of a gene family with GPA and GPB genes. This encoded protein might carry the M blood group antigen. GYPA, GYPB, and GYPE are organized in tandem on chromosome 4. This gene might have derived from an ancestral gene common to the GPB gene by gene duplication. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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