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Anti-IFM5/ IFI™5/ BRIL monoclonal antibody
Anti-IFM5/ IFI™5/ BRIL antibody for FACS & in-vivo assay
Go to IFI™5/IFI™5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0606-Ab-1/ GM-Tg-hg-MP0606-Ab-2 | Anti-Human IFI™5 monoclonal antibody | Human |
| GM-Tg-rg-MP0606-Ab-1/ GM-Tg-rg-MP0606-Ab-2 | Anti-Rat IFI™5 monoclonal antibody | Rat |
| GM-Tg-mg-MP0606-Ab-1/ GM-Tg-mg-MP0606-Ab-2 | Anti-Mouse IFI™5 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0606-Ab-1/ GM-Tg-cynog-MP0606-Ab-2 | Anti-Cynomolgus/ Rhesus macaque IFI™5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0606-Ab-1/ GM-Tg-felg-MP0606-Ab-2 | Anti-Feline IFI™5 monoclonal antibody | Feline |
| GM-Tg-cang-MP0606-Ab-1/ GM-Tg-cang-MP0606-Ab-2 | Anti-Canine IFI™5 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0606-Ab-1/ GM-Tg-bovg-MP0606-Ab-2 | Anti-Bovine IFI™5 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0606-Ab-1/ GM-Tg-equg-MP0606-Ab-2 | Anti-Equine IFI™5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0606-Ab-1/ GM-Tg-hg-MP0606-Ab-2; GM-Tg-rg-MP0606-Ab-1/ GM-Tg-rg-MP0606-Ab-2; GM-Tg-mg-MP0606-Ab-1/ GM-Tg-mg-MP0606-Ab-2; GM-Tg-cynog-MP0606-Ab-1/ GM-Tg-cynog-MP0606-Ab-2; GM-Tg-felg-MP0606-Ab-1/ GM-Tg-felg-MP0606-Ab-2; GM-Tg-cang-MP0606-Ab-1/ GM-Tg-cang-MP0606-Ab-2; GM-Tg-bovg-MP0606-Ab-1/ GM-Tg-bovg-MP0606-Ab-2; GM-Tg-equg-MP0606-Ab-1/ GM-Tg-equg-MP0606-Ab-2 |
| Products Name | Anti-IFI™5 monoclonal antibody |
| Format | mab |
| Target Name | IFI™5 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IFI™5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species IFM5/ IFI™5/ BRIL VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP001871 | human IFI™5 Lentivirus plasmid |
| ORF Viral Vector | vGMLP000848 | human IFI™5 Lentivirus particle |
| ORF Viral Vector | vGMLP001871 | human IFI™5 Lentivirus particle |
| ORF Viral Vector | pGMLP000848 | human IFI™5 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm001001 | mouse Ifitm5 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001001 | mouse Ifitm5 Lentivirus particle |
Target information
| Target ID | GM-MP0606 |
| Target Name | IFI™5 |
| Gene ID | 387733,73835,293617,697314,119864192,101101083,526461,100050873 |
| Gene Symbol and Synonyms | 1110003J06Rik,BRIL,DSPA1,fragilis4,Hrmp1,Hrtm1,IFI™5,OI5 |
| Uniprot Accession | A6NNB3 |
| Uniprot Entry Name | IFM5_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000206013 |
| Target Classification | N/A |
The target: IFI™5, gene name: IFI™5, also named as BRIL, DSPA1, Hrmp1, OI5, fragilis4. This gene encodes a membrane protein thought to play a role in bone mineralization. This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195). [provided by RefSeq, Aug 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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