- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-I22R2/ IL22RA2/ CRF2-10 monoclonal antibody
Anti-I22R2/ IL22RA2/ CRF2-10 antibody for FACS & in-vivo assay
Go to IL22RA2/IL22RA2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0626-Ab-1/ GM-Tg-hg-MP0626-Ab-2 | Anti-Human IL22RA2 monoclonal antibody | Human |
| GM-Tg-rg-MP0626-Ab-1/ GM-Tg-rg-MP0626-Ab-2 | Anti-Rat IL22RA2 monoclonal antibody | Rat |
| GM-Tg-mg-MP0626-Ab-1/ GM-Tg-mg-MP0626-Ab-2 | Anti-Mouse IL22RA2 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0626-Ab-1/ GM-Tg-cynog-MP0626-Ab-2 | Anti-Cynomolgus/ Rhesus macaque IL22RA2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0626-Ab-1/ GM-Tg-felg-MP0626-Ab-2 | Anti-Feline IL22RA2 monoclonal antibody | Feline |
| GM-Tg-cang-MP0626-Ab-1/ GM-Tg-cang-MP0626-Ab-2 | Anti-Canine IL22RA2 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0626-Ab-1/ GM-Tg-bovg-MP0626-Ab-2 | Anti-Bovine IL22RA2 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0626-Ab-1/ GM-Tg-equg-MP0626-Ab-2 | Anti-Equine IL22RA2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0626-Ab-1/ GM-Tg-hg-MP0626-Ab-2; GM-Tg-rg-MP0626-Ab-1/ GM-Tg-rg-MP0626-Ab-2; GM-Tg-mg-MP0626-Ab-1/ GM-Tg-mg-MP0626-Ab-2; GM-Tg-cynog-MP0626-Ab-1/ GM-Tg-cynog-MP0626-Ab-2; GM-Tg-felg-MP0626-Ab-1/ GM-Tg-felg-MP0626-Ab-2; GM-Tg-cang-MP0626-Ab-1/ GM-Tg-cang-MP0626-Ab-2; GM-Tg-bovg-MP0626-Ab-1/ GM-Tg-bovg-MP0626-Ab-2; GM-Tg-equg-MP0626-Ab-1/ GM-Tg-equg-MP0626-Ab-2 |
| Products Name | Anti-IL22RA2 monoclonal antibody |
| Format | mab |
| Target Name | IL22RA2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IL22RA2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species I22R2/ IL22RA2/ CRF2-10 VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-MP0626-Ag-1 | interleukin 22 receptor, alpha 2 (IL22RA2) protein |
Target information
| Target ID | GM-MP0626 |
| Target Name | IL22RA2 |
| Gene ID | 116379,237310,444986,711059,100856046,101083429,533061,100073194 |
| Gene Symbol and Synonyms | CRF2-10,CRF2-S1,CRF2X,IL-22BP,IL-22R-alpha-2,IL-22RA2,IL22RA2,ZCYTOR16 |
| Uniprot Accession | Q969J5,Q7TNI4 |
| Uniprot Entry Name | I22R2_HUMAN,I22R2_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000164485 |
| Target Classification | N/A |
The target: IL22RA2, gene name: IL22RA2, also named as CRF2-10, CRF2-S1, CRF2X, IL-22BP, IL-22R-alpha-2, IL-22RA2, ZCYTOR16. This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
