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Anti-LRIG2/ LIG-2/ LIG2 monoclonal antibody
Anti-LRIG2/ LIG-2/ LIG2 antibody for FACS & in-vivo assay
Go to LRIG2/LRIG2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0750-Ab-1/ GM-Tg-hg-MP0750-Ab-2 | Anti-Human LRIG2 monoclonal antibody | Human |
| GM-Tg-rg-MP0750-Ab-1/ GM-Tg-rg-MP0750-Ab-2 | Anti-Rat LRIG2 monoclonal antibody | Rat |
| GM-Tg-mg-MP0750-Ab-1/ GM-Tg-mg-MP0750-Ab-2 | Anti-Mouse LRIG2 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0750-Ab-1/ GM-Tg-cynog-MP0750-Ab-2 | Anti-Cynomolgus/ Rhesus macaque LRIG2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0750-Ab-1/ GM-Tg-felg-MP0750-Ab-2 | Anti-Feline LRIG2 monoclonal antibody | Feline |
| GM-Tg-cang-MP0750-Ab-1/ GM-Tg-cang-MP0750-Ab-2 | Anti-Canine LRIG2 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0750-Ab-1/ GM-Tg-bovg-MP0750-Ab-2 | Anti-Bovine LRIG2 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0750-Ab-1/ GM-Tg-equg-MP0750-Ab-2 | Anti-Equine LRIG2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0750-Ab-1/ GM-Tg-hg-MP0750-Ab-2; GM-Tg-rg-MP0750-Ab-1/ GM-Tg-rg-MP0750-Ab-2; GM-Tg-mg-MP0750-Ab-1/ GM-Tg-mg-MP0750-Ab-2; GM-Tg-cynog-MP0750-Ab-1/ GM-Tg-cynog-MP0750-Ab-2; GM-Tg-felg-MP0750-Ab-1/ GM-Tg-felg-MP0750-Ab-2; GM-Tg-cang-MP0750-Ab-1/ GM-Tg-cang-MP0750-Ab-2; GM-Tg-bovg-MP0750-Ab-1/ GM-Tg-bovg-MP0750-Ab-2; GM-Tg-equg-MP0750-Ab-1/ GM-Tg-equg-MP0750-Ab-2 |
| Products Name | Anti-LRIG2 monoclonal antibody |
| Format | mab |
| Target Name | LRIG2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-LRIG2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species LRIG2/ LIG-2/ LIG2 VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-MP0750-Ag-1 | leucine-rich repeats and immunoglobulin-like domains 2 (LRIG2) protein |
Target information
| Target ID | GM-MP0750 |
| Target Name | LRIG2 |
| Gene ID | 9860,269473,310753,706897,483215,101099316,535493,100064414 |
| Gene Symbol and Synonyms | 4632419I10Rik,LIG-2,LIG2,LRIG2,UFS2 |
| Uniprot Accession | O94898 |
| Uniprot Entry Name | LRIG2_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000198799 |
| Target Classification | N/A |
The target: LRIG2, gene name: LRIG2, also named as LIG-2, LIG2, UFS2. This gene encodes a transmembrane protein containing leucine-rich repeats and immunoglobulin-like domains. The encoded protein promotes epidermal growth factor signalling, resulting in increased proliferation. Its expression in the cytoplasm of glioma cells is correlated with poor survival. Mutations in this gene can cause urofacial syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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