Anti-EMC5/ MMGT1/ ™EM32 monoclonal antibody

Anti-EMC5/ MMGT1/ ™EM32 antibody for FACS & in-vivo assay

Target products collectionGo to MMGT1/MMGT1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0819-Ab-1/ GM-Tg-hg-MP0819-Ab-2Anti-Human MMGT1 monoclonal antibodyHuman
GM-Tg-rg-MP0819-Ab-1/ GM-Tg-rg-MP0819-Ab-2Anti-Rat MMGT1 monoclonal antibodyRat
GM-Tg-mg-MP0819-Ab-1/ GM-Tg-mg-MP0819-Ab-2Anti-Mouse MMGT1 monoclonal antibodyMouse
GM-Tg-cynog-MP0819-Ab-1/ GM-Tg-cynog-MP0819-Ab-2Anti-Cynomolgus/ Rhesus macaque MMGT1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0819-Ab-1/ GM-Tg-felg-MP0819-Ab-2Anti-Feline MMGT1 monoclonal antibodyFeline
GM-Tg-cang-MP0819-Ab-1/ GM-Tg-cang-MP0819-Ab-2Anti-Canine MMGT1 monoclonal antibodyCanine
GM-Tg-bovg-MP0819-Ab-1/ GM-Tg-bovg-MP0819-Ab-2Anti-Bovine MMGT1 monoclonal antibodyBovine
GM-Tg-equg-MP0819-Ab-1/ GM-Tg-equg-MP0819-Ab-2Anti-Equine MMGT1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0819-Ab-1/ GM-Tg-hg-MP0819-Ab-2; GM-Tg-rg-MP0819-Ab-1/ GM-Tg-rg-MP0819-Ab-2;
GM-Tg-mg-MP0819-Ab-1/ GM-Tg-mg-MP0819-Ab-2; GM-Tg-cynog-MP0819-Ab-1/ GM-Tg-cynog-MP0819-Ab-2;
GM-Tg-felg-MP0819-Ab-1/ GM-Tg-felg-MP0819-Ab-2; GM-Tg-cang-MP0819-Ab-1/ GM-Tg-cang-MP0819-Ab-2;
GM-Tg-bovg-MP0819-Ab-1/ GM-Tg-bovg-MP0819-Ab-2; GM-Tg-equg-MP0819-Ab-1/ GM-Tg-equg-MP0819-Ab-2
Products NameAnti-MMGT1 monoclonal antibody
Formatmab
Target NameMMGT1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MMGT1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species EMC5/ MMGT1/ ™EM32 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP000402human MMGT1 Lentivirus plasmid
    ORF Viral VectorvGMLP000402human MMGT1 Lentivirus particle


    Target information

    Target IDGM-MP0819
    Target NameMMGT1
    Gene ID93380,236792,302864,710338,611935,101097549,617557,100054769
    Gene Symbol and Synonyms9630048L06Rik,EMC5,mir-5116,Mir5116,MMGT1,RGD1566339,™EM32
    Uniprot AccessionQ8N4V1,B5DF51,Q32LC4
    Uniprot Entry NameEMC5_HUMAN,EMC5_RAT,EMC5_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000169446
    Target ClassificationN/A

    The target: MMGT1, gene name: MMGT1, also named as EMC5, ™EM32. Contributes to membrane insertase activity. Involved in protein insertion into ER membrane by stop-transfer membrane-anchor sequence and tail-anchored membrane protein insertion into ER membrane. Is integral component of endoplasmic reticulum membrane. Part of EMC complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.