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Anti-MRAP2/ C6orf117/ bA51G5.2 monoclonal antibody
Anti-MRAP2/ C6orf117/ bA51G5.2 antibody for FACS & in-vivo assay
Go to MRAP2/MRAP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0829-Ab-1/ GM-Tg-hg-MP0829-Ab-2 | Anti-Human MRAP2 monoclonal antibody | Human |
| GM-Tg-rg-MP0829-Ab-1/ GM-Tg-rg-MP0829-Ab-2 | Anti-Rat MRAP2 monoclonal antibody | Rat |
| GM-Tg-mg-MP0829-Ab-1/ GM-Tg-mg-MP0829-Ab-2 | Anti-Mouse MRAP2 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0829-Ab-1/ GM-Tg-cynog-MP0829-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MRAP2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0829-Ab-1/ GM-Tg-felg-MP0829-Ab-2 | Anti-Feline MRAP2 monoclonal antibody | Feline |
| GM-Tg-cang-MP0829-Ab-1/ GM-Tg-cang-MP0829-Ab-2 | Anti-Canine MRAP2 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0829-Ab-1/ GM-Tg-bovg-MP0829-Ab-2 | Anti-Bovine MRAP2 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0829-Ab-1/ GM-Tg-equg-MP0829-Ab-2 | Anti-Equine MRAP2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0829-Ab-1/ GM-Tg-hg-MP0829-Ab-2; GM-Tg-rg-MP0829-Ab-1/ GM-Tg-rg-MP0829-Ab-2; GM-Tg-mg-MP0829-Ab-1/ GM-Tg-mg-MP0829-Ab-2; GM-Tg-cynog-MP0829-Ab-1/ GM-Tg-cynog-MP0829-Ab-2; GM-Tg-felg-MP0829-Ab-1/ GM-Tg-felg-MP0829-Ab-2; GM-Tg-cang-MP0829-Ab-1/ GM-Tg-cang-MP0829-Ab-2; GM-Tg-bovg-MP0829-Ab-1/ GM-Tg-bovg-MP0829-Ab-2; GM-Tg-equg-MP0829-Ab-1/ GM-Tg-equg-MP0829-Ab-2 |
| Products Name | Anti-MRAP2 monoclonal antibody |
| Format | mab |
| Target Name | MRAP2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MRAP2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species MRAP2/ C6orf117/ bA51G5.2 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP004128 | human MRAP2 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004128 | human MRAP2 Lentivirus particle |
| ORF Viral Vector | pGMLPm003303 | mouse Mrap2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003303 | mouse Mrap2 Lentivirus particle |
Target information
| Target ID | GM-MP0829 |
| Target Name | MRAP2 |
| Gene ID | 112609,244958,363112,611524,101083426,781188,100065482 |
| Gene Symbol and Synonyms | bA51G5.2,C6orf117,C9H6ORF117,MRAP2,RGD1309873 |
| Uniprot Accession | Q96G30 |
| Uniprot Entry Name | MRAP2_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000135324 |
| Target Classification | N/A |
The target: MRAP2, gene name: MRAP2, also named as C6orf117, bA51G5.2. This gene encodes a protein that modulates melanocortin receptor signaling. The encoded protein has been shown to interact with all known melanocortin receptors and may regulate both receptor trafficking and activation in response to ligands. Mice lacking a functional copy of this gene exhibit severe obesity and a mutation in this gene may be associated with severe obesity in human patients. [provided by RefSeq, Oct 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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