Anti-MRGX3/ MRGPRX3/ GPCR monoclonal antibody

Anti-MRGX3/ MRGPRX3/ GPCR antibody for FACS & in-vivo assay

Target products collectionGo to MRGPRX3/MRGPRX3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0834-Ab-1/ GM-Tg-hg-MP0834-Ab-2Anti-Human MRGPRX3 monoclonal antibodyHuman
GM-Tg-rg-MP0834-Ab-1/ GM-Tg-rg-MP0834-Ab-2Anti-Rat MRGPRX3 monoclonal antibodyRat
GM-Tg-mg-MP0834-Ab-1/ GM-Tg-mg-MP0834-Ab-2Anti-Mouse MRGPRX3 monoclonal antibodyMouse
GM-Tg-cynog-MP0834-Ab-1/ GM-Tg-cynog-MP0834-Ab-2Anti-Cynomolgus/ Rhesus macaque MRGPRX3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0834-Ab-1/ GM-Tg-felg-MP0834-Ab-2Anti-Feline MRGPRX3 monoclonal antibodyFeline
GM-Tg-cang-MP0834-Ab-1/ GM-Tg-cang-MP0834-Ab-2Anti-Canine MRGPRX3 monoclonal antibodyCanine
GM-Tg-bovg-MP0834-Ab-1/ GM-Tg-bovg-MP0834-Ab-2Anti-Bovine MRGPRX3 monoclonal antibodyBovine
GM-Tg-equg-MP0834-Ab-1/ GM-Tg-equg-MP0834-Ab-2Anti-Equine MRGPRX3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0834-Ab-1/ GM-Tg-hg-MP0834-Ab-2; GM-Tg-rg-MP0834-Ab-1/ GM-Tg-rg-MP0834-Ab-2;
GM-Tg-mg-MP0834-Ab-1/ GM-Tg-mg-MP0834-Ab-2; GM-Tg-cynog-MP0834-Ab-1/ GM-Tg-cynog-MP0834-Ab-2;
GM-Tg-felg-MP0834-Ab-1/ GM-Tg-felg-MP0834-Ab-2; GM-Tg-cang-MP0834-Ab-1/ GM-Tg-cang-MP0834-Ab-2;
GM-Tg-bovg-MP0834-Ab-1/ GM-Tg-bovg-MP0834-Ab-2; GM-Tg-equg-MP0834-Ab-1/ GM-Tg-equg-MP0834-Ab-2
Products NameAnti-MRGPRX3 monoclonal antibody
Formatmab
Target NameMRGPRX3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MRGPRX3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MRGX3/ MRGPRX3/ GPCR VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP004680human GPCR Lentivirus plasmid
    ORF Viral VectorvGMLP004680human GPCR Lentivirus particle


    Target information

    Target IDGM-MP0834
    Target NameMRGPRX3
    Gene ID117195
    Gene Symbol and SynonymsGPCR,MRGPRX3,MRGX3,SNSR1,SNSR2
    Uniprot AccessionQ96LB0
    Uniprot Entry NameMRGX3_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000179826
    Target ClassificationGPCR

    The target: MRGPRX3, gene name: MRGPRX3, also named as GPCR, MRGX3, SNSR1, SNSR2. This gene encodes a member of the mas-related/sensory neuron specific subfamily of G protein coupled receptors. The encoded protein may be involved in sensory neuron regulation and in the modulation of pain. [provided by RefSeq, Oct 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.