Anti-NCTR2/ NCR2/ CD336 monoclonal antibody

Anti-NCTR2/ NCR2/ CD336 antibody for FACS & in-vivo assay

Target products collectionGo to NCR2/NCR2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0868-Ab-1/ GM-Tg-hg-MP0868-Ab-2Anti-Human NCR2 monoclonal antibodyHuman
GM-Tg-rg-MP0868-Ab-1/ GM-Tg-rg-MP0868-Ab-2Anti-Rat NCR2 monoclonal antibodyRat
GM-Tg-mg-MP0868-Ab-1/ GM-Tg-mg-MP0868-Ab-2Anti-Mouse NCR2 monoclonal antibodyMouse
GM-Tg-cynog-MP0868-Ab-1/ GM-Tg-cynog-MP0868-Ab-2Anti-Cynomolgus/ Rhesus macaque NCR2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0868-Ab-1/ GM-Tg-felg-MP0868-Ab-2Anti-Feline NCR2 monoclonal antibodyFeline
GM-Tg-cang-MP0868-Ab-1/ GM-Tg-cang-MP0868-Ab-2Anti-Canine NCR2 monoclonal antibodyCanine
GM-Tg-bovg-MP0868-Ab-1/ GM-Tg-bovg-MP0868-Ab-2Anti-Bovine NCR2 monoclonal antibodyBovine
GM-Tg-equg-MP0868-Ab-1/ GM-Tg-equg-MP0868-Ab-2Anti-Equine NCR2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0868-Ab-1/ GM-Tg-hg-MP0868-Ab-2; GM-Tg-rg-MP0868-Ab-1/ GM-Tg-rg-MP0868-Ab-2;
GM-Tg-mg-MP0868-Ab-1/ GM-Tg-mg-MP0868-Ab-2; GM-Tg-cynog-MP0868-Ab-1/ GM-Tg-cynog-MP0868-Ab-2;
GM-Tg-felg-MP0868-Ab-1/ GM-Tg-felg-MP0868-Ab-2; GM-Tg-cang-MP0868-Ab-1/ GM-Tg-cang-MP0868-Ab-2;
GM-Tg-bovg-MP0868-Ab-1/ GM-Tg-bovg-MP0868-Ab-2; GM-Tg-equg-MP0868-Ab-1/ GM-Tg-equg-MP0868-Ab-2
Products NameAnti-NCR2 monoclonal antibody
Formatmab
Target NameNCR2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-NCR2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species NCTR2/ NCR2/ CD336 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP004963human NCR2 Lentivirus plasmid
    ORF Viral VectorvGMLP004963human NCR2 Lentivirus particle


    Target information

    Target IDGM-MP0868
    Target NameNCR2
    Gene ID9436,693869,101090864,100066291
    Gene Symbol and SynonymsCD336,dJ149M18.1,LY95,NCR2,NK-p44,NKP44
    Uniprot AccessionO95944
    Uniprot Entry NameNCTR2_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000096264
    Target ClassificationN/A

    The target: NCR2, gene name: NCR2, also named as CD336, LY95, NK-p44, NKP44, dJ149M18.1. Predicted to enable signaling receptor activity. Predicted to be involved in cellular defense response and signal transduction. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Predicted to be active in cell surface. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.