- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-NIPA1/ FSP3/ SLC57A1 monoclonal antibody
Anti-NIPA1/ FSP3/ SLC57A1 antibody for FACS & in-vivo assay
Go to NIPA1/NIPA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0878-Ab-1/ GM-Tg-hg-MP0878-Ab-2 | Anti-Human NIPA1 monoclonal antibody | Human |
| GM-Tg-rg-MP0878-Ab-1/ GM-Tg-rg-MP0878-Ab-2 | Anti-Rat NIPA1 monoclonal antibody | Rat |
| GM-Tg-mg-MP0878-Ab-1/ GM-Tg-mg-MP0878-Ab-2 | Anti-Mouse NIPA1 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0878-Ab-1/ GM-Tg-cynog-MP0878-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NIPA1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0878-Ab-1/ GM-Tg-felg-MP0878-Ab-2 | Anti-Feline NIPA1 monoclonal antibody | Feline |
| GM-Tg-cang-MP0878-Ab-1/ GM-Tg-cang-MP0878-Ab-2 | Anti-Canine NIPA1 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0878-Ab-1/ GM-Tg-bovg-MP0878-Ab-2 | Anti-Bovine NIPA1 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0878-Ab-1/ GM-Tg-equg-MP0878-Ab-2 | Anti-Equine NIPA1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0878-Ab-1/ GM-Tg-hg-MP0878-Ab-2; GM-Tg-rg-MP0878-Ab-1/ GM-Tg-rg-MP0878-Ab-2; GM-Tg-mg-MP0878-Ab-1/ GM-Tg-mg-MP0878-Ab-2; GM-Tg-cynog-MP0878-Ab-1/ GM-Tg-cynog-MP0878-Ab-2; GM-Tg-felg-MP0878-Ab-1/ GM-Tg-felg-MP0878-Ab-2; GM-Tg-cang-MP0878-Ab-1/ GM-Tg-cang-MP0878-Ab-2; GM-Tg-bovg-MP0878-Ab-1/ GM-Tg-bovg-MP0878-Ab-2; GM-Tg-equg-MP0878-Ab-1/ GM-Tg-equg-MP0878-Ab-2 |
| Products Name | Anti-NIPA1 monoclonal antibody |
| Format | mab |
| Target Name | NIPA1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-NIPA1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species NIPA1/ FSP3/ SLC57A1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP004947 | human NIPA1 Lentivirus particle |
| ORF Viral Vector | pGMLP004947 | human NIPA1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004554 | mouse Nipa1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004554 | mouse Nipa1 Lentivirus particle |
Target information
| Target ID | GM-MP0878 |
| Target Name | NIPA1 |
| Gene ID | 123606,233280,308668,710236,488681,101090753,539162,100146592 |
| Gene Symbol and Synonyms | 1110027G09Rik,A830014A18Rik,FSP3,NIPA1,SLC56A1,SLC57A1,SPG6 |
| Uniprot Accession | Q7RTP0 |
| Uniprot Entry Name | NIPA1_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000170113 |
| Target Classification | N/A |
The target: NIPA1, gene name: NIPA1, also named as FSP3, SLC57A1, SPG6. This gene encodes a magnesium transporter that associates with early endosomes and the cell surface in a variety of neuronal and epithelial cells. This protein may play a role in nervous system development and maintenance. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with autosomal dominant spastic paraplegia 6. [provided by RefSeq, Nov 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
