Anti-OPALI/ OPALIN/ H™P10 monoclonal antibody

Anti-OPALI/ OPALIN/ H™P10 antibody for FACS & in-vivo assay

Target products collectionGo to OPALIN/OPALIN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0919-Ab-1/ GM-Tg-hg-MP0919-Ab-2Anti-Human OPALIN monoclonal antibodyHuman
GM-Tg-rg-MP0919-Ab-1/ GM-Tg-rg-MP0919-Ab-2Anti-Rat OPALIN monoclonal antibodyRat
GM-Tg-mg-MP0919-Ab-1/ GM-Tg-mg-MP0919-Ab-2Anti-Mouse OPALIN monoclonal antibodyMouse
GM-Tg-cynog-MP0919-Ab-1/ GM-Tg-cynog-MP0919-Ab-2Anti-Cynomolgus/ Rhesus macaque OPALIN monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0919-Ab-1/ GM-Tg-felg-MP0919-Ab-2Anti-Feline OPALIN monoclonal antibodyFeline
GM-Tg-cang-MP0919-Ab-1/ GM-Tg-cang-MP0919-Ab-2Anti-Canine OPALIN monoclonal antibodyCanine
GM-Tg-bovg-MP0919-Ab-1/ GM-Tg-bovg-MP0919-Ab-2Anti-Bovine OPALIN monoclonal antibodyBovine
GM-Tg-equg-MP0919-Ab-1/ GM-Tg-equg-MP0919-Ab-2Anti-Equine OPALIN monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0919-Ab-1/ GM-Tg-hg-MP0919-Ab-2; GM-Tg-rg-MP0919-Ab-1/ GM-Tg-rg-MP0919-Ab-2;
GM-Tg-mg-MP0919-Ab-1/ GM-Tg-mg-MP0919-Ab-2; GM-Tg-cynog-MP0919-Ab-1/ GM-Tg-cynog-MP0919-Ab-2;
GM-Tg-felg-MP0919-Ab-1/ GM-Tg-felg-MP0919-Ab-2; GM-Tg-cang-MP0919-Ab-1/ GM-Tg-cang-MP0919-Ab-2;
GM-Tg-bovg-MP0919-Ab-1/ GM-Tg-bovg-MP0919-Ab-2; GM-Tg-equg-MP0919-Ab-1/ GM-Tg-equg-MP0919-Ab-2
Products NameAnti-OPALIN monoclonal antibody
Formatmab
Target NameOPALIN
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-OPALIN benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species OPALI/ OPALIN/ H™P10 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP004392human OPALIN Lentivirus plasmid
    ORF Viral VectorvGMLP004392human OPALIN Lentivirus particle
    ORF Viral VectorpGMLPm004267mouse Opalin Lentivirus plasmid
    ORF Viral VectorvGMLPm004267mouse Opalin Lentivirus particle


    Target information

    Target IDGM-MP0919
    Target NameOPALIN
    Gene ID93377,226115,361757,704725,608634,101097350,616443,100630111
    Gene Symbol and SynonymsH™P10,OPALIN,™EM10,™P10
    Uniprot AccessionQ96PE5,Q5E9I3
    Uniprot Entry NameOPALI_HUMAN,OPALI_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000197430
    Target ClassificationN/A

    The target: OPALIN, gene name: OPALIN, also named as H™P10, ™EM10, ™P10. Predicted to be involved in regulation of oligodendrocyte differentiation. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.