Anti-PAQR7/ MPRA/ PGLP monoclonal antibody

Anti-PAQR7/ MPRA/ PGLP antibody for FACS & in-vivo assay

Target products collectionGo to PAQR7/PAQR7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1317-Ab-1/ GM-Tg-hg-MP1317-Ab-2Anti-Human PAQR7 monoclonal antibodyHuman
GM-Tg-rg-MP1317-Ab-1/ GM-Tg-rg-MP1317-Ab-2Anti-Rat PAQR7 monoclonal antibodyRat
GM-Tg-mg-MP1317-Ab-1/ GM-Tg-mg-MP1317-Ab-2Anti-Mouse PAQR7 monoclonal antibodyMouse
GM-Tg-cynog-MP1317-Ab-1/ GM-Tg-cynog-MP1317-Ab-2Anti-Cynomolgus/ Rhesus macaque PAQR7 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1317-Ab-1/ GM-Tg-felg-MP1317-Ab-2Anti-Feline PAQR7 monoclonal antibodyFeline
GM-Tg-cang-MP1317-Ab-1/ GM-Tg-cang-MP1317-Ab-2Anti-Canine PAQR7 monoclonal antibodyCanine
GM-Tg-bovg-MP1317-Ab-1/ GM-Tg-bovg-MP1317-Ab-2Anti-Bovine PAQR7 monoclonal antibodyBovine
GM-Tg-equg-MP1317-Ab-1/ GM-Tg-equg-MP1317-Ab-2Anti-Equine PAQR7 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1317-Ab-1/ GM-Tg-hg-MP1317-Ab-2; GM-Tg-rg-MP1317-Ab-1/ GM-Tg-rg-MP1317-Ab-2;
GM-Tg-mg-MP1317-Ab-1/ GM-Tg-mg-MP1317-Ab-2; GM-Tg-cynog-MP1317-Ab-1/ GM-Tg-cynog-MP1317-Ab-2;
GM-Tg-felg-MP1317-Ab-1/ GM-Tg-felg-MP1317-Ab-2; GM-Tg-cang-MP1317-Ab-1/ GM-Tg-cang-MP1317-Ab-2;
GM-Tg-bovg-MP1317-Ab-1/ GM-Tg-bovg-MP1317-Ab-2; GM-Tg-equg-MP1317-Ab-1/ GM-Tg-equg-MP1317-Ab-2
Products NameAnti-PAQR7 monoclonal antibody
Formatmab
Target NamePAQR7
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PAQR7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PAQR7/ MPRA/ PGLP VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP003567human PAQR7 Lentivirus plasmid
    ORF Viral VectorvGMLP003567human PAQR7 Lentivirus particle
    ORF Viral VectorpGMLPm002065mouse Paqr7 Lentivirus plasmid
    ORF Viral VectorvGMLPm002065mouse Paqr7 Lentivirus particle


    Target information

    Target IDGM-MP1317
    Target NamePAQR7
    Gene ID164091,71904,313615,713411,487364,101082327,522932,100071257
    Gene Symbol and Synonyms2310021M12Rik,mPR,mPR alpha,MPRA,mSR,PAQR7,PGLP
    Uniprot AccessionQ86WK9
    Uniprot Entry NamePAQR7_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000182749
    Target ClassificationN/A

    The target: PAQR7, gene name: PAQR7, also named as MPRA, PGLP, mSR. Predicted to enable steroid binding activity and steroid hormone receptor activity. Predicted to be involved in response to steroid hormone. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.