Anti-PAQR7/ MPRA/ PGLP monoclonal antibody
Anti-PAQR7/ MPRA/ PGLP antibody for FACS & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-MP1317-Ab-1/ GM-Tg-hg-MP1317-Ab-2 | Anti-Human PAQR7 monoclonal antibody | Human |
GM-Tg-rg-MP1317-Ab-1/ GM-Tg-rg-MP1317-Ab-2 | Anti-Rat PAQR7 monoclonal antibody | Rat |
GM-Tg-mg-MP1317-Ab-1/ GM-Tg-mg-MP1317-Ab-2 | Anti-Mouse PAQR7 monoclonal antibody | Mouse |
GM-Tg-cynog-MP1317-Ab-1/ GM-Tg-cynog-MP1317-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PAQR7 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-MP1317-Ab-1/ GM-Tg-felg-MP1317-Ab-2 | Anti-Feline PAQR7 monoclonal antibody | Feline |
GM-Tg-cang-MP1317-Ab-1/ GM-Tg-cang-MP1317-Ab-2 | Anti-Canine PAQR7 monoclonal antibody | Canine |
GM-Tg-bovg-MP1317-Ab-1/ GM-Tg-bovg-MP1317-Ab-2 | Anti-Bovine PAQR7 monoclonal antibody | Bovine |
GM-Tg-equg-MP1317-Ab-1/ GM-Tg-equg-MP1317-Ab-2 | Anti-Equine PAQR7 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-MP1317-Ab-1/ GM-Tg-hg-MP1317-Ab-2; GM-Tg-rg-MP1317-Ab-1/ GM-Tg-rg-MP1317-Ab-2; GM-Tg-mg-MP1317-Ab-1/ GM-Tg-mg-MP1317-Ab-2; GM-Tg-cynog-MP1317-Ab-1/ GM-Tg-cynog-MP1317-Ab-2; GM-Tg-felg-MP1317-Ab-1/ GM-Tg-felg-MP1317-Ab-2; GM-Tg-cang-MP1317-Ab-1/ GM-Tg-cang-MP1317-Ab-2; GM-Tg-bovg-MP1317-Ab-1/ GM-Tg-bovg-MP1317-Ab-2; GM-Tg-equg-MP1317-Ab-1/ GM-Tg-equg-MP1317-Ab-2 |
Products Name | Anti-PAQR7 monoclonal antibody |
Format | mab |
Target Name | PAQR7 |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-PAQR7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | Products Developing | Multi-species PAQR7/ MPRA/ PGLP VLP (virus-like particle) (Products Developing) |
ORF Viral Vector | pGMLP003567 | human PAQR7 Lentivirus plasmid |
ORF Viral Vector | vGMLP003567 | human PAQR7 Lentivirus particle |
ORF Viral Vector | pGMLPm002065 | mouse Paqr7 Lentivirus plasmid |
ORF Viral Vector | vGMLPm002065 | mouse Paqr7 Lentivirus particle |
Target information
Target ID | GM-MP1317 |
Target Name | PAQR7 |
Gene ID | 164091,71904,313615,713411,487364,101082327,522932,100071257 |
Gene Symbol and Synonyms | 2310021M12Rik,mPR,mPR alpha,MPRA,mSR,PAQR7,PGLP |
Uniprot Accession | Q86WK9 |
Uniprot Entry Name | PAQR7_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000182749 |
Target Classification | N/A |
The target: PAQR7, gene name: PAQR7, also named as MPRA, PGLP, mSR. Predicted to enable steroid binding activity and steroid hormone receptor activity. Predicted to be involved in response to steroid hormone. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.