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Anti-PIRT monoclonal antibody
Anti-PIRT antibody for FACS & in-vivo assay
Go to PIRT/PIRT products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1373-Ab-1/ GM-Tg-hg-MP1373-Ab-2 | Anti-Human PIRT monoclonal antibody | Human |
| GM-Tg-rg-MP1373-Ab-1/ GM-Tg-rg-MP1373-Ab-2 | Anti-Rat PIRT monoclonal antibody | Rat |
| GM-Tg-mg-MP1373-Ab-1/ GM-Tg-mg-MP1373-Ab-2 | Anti-Mouse PIRT monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1373-Ab-1/ GM-Tg-cynog-MP1373-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PIRT monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1373-Ab-1/ GM-Tg-felg-MP1373-Ab-2 | Anti-Feline PIRT monoclonal antibody | Feline |
| GM-Tg-cang-MP1373-Ab-1/ GM-Tg-cang-MP1373-Ab-2 | Anti-Canine PIRT monoclonal antibody | Canine |
| GM-Tg-bovg-MP1373-Ab-1/ GM-Tg-bovg-MP1373-Ab-2 | Anti-Bovine PIRT monoclonal antibody | Bovine |
| GM-Tg-equg-MP1373-Ab-1/ GM-Tg-equg-MP1373-Ab-2 | Anti-Equine PIRT monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1373-Ab-1/ GM-Tg-hg-MP1373-Ab-2; GM-Tg-rg-MP1373-Ab-1/ GM-Tg-rg-MP1373-Ab-2; GM-Tg-mg-MP1373-Ab-1/ GM-Tg-mg-MP1373-Ab-2; GM-Tg-cynog-MP1373-Ab-1/ GM-Tg-cynog-MP1373-Ab-2; GM-Tg-felg-MP1373-Ab-1/ GM-Tg-felg-MP1373-Ab-2; GM-Tg-cang-MP1373-Ab-1/ GM-Tg-cang-MP1373-Ab-2; GM-Tg-bovg-MP1373-Ab-1/ GM-Tg-bovg-MP1373-Ab-2; GM-Tg-equg-MP1373-Ab-1/ GM-Tg-equg-MP1373-Ab-2 |
| Products Name | Anti-PIRT monoclonal antibody |
| Format | mab |
| Target Name | PIRT |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PIRT benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species PIRT VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP001830 | human PIRT Lentivirus particle |
| ORF Viral Vector | pGMLP001830 | human PIRT Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000806 | mouse Pirt Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000806 | mouse Pirt Lentivirus particle |
Target information
| Target ID | GM-MP1373 |
| Target Name | PIRT |
| Gene ID | 644139,193003,497929,722083,100686498,101085672,100140752,100063035 |
| Gene Symbol and Synonyms | A530088H08Rik,PIRT,RGD1565284 |
| Uniprot Accession | P0C851 |
| Uniprot Entry Name | PIRT_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000233670 |
| Target Classification | N/A |
The target: PIRT, gene name: PIRT, also named as . Predicted to enable phosphatidylinositol bisphosphate binding activity and transmembrane transporter binding activity. Predicted to be involved in phosphatidylinositol-mediated signaling and positive regulation of cation channel activity. Predicted to act upstream of or within behavioral response to pain and response to heat. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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