- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-™G1/ PRRG1/ PRGP1 monoclonal antibody
Anti-™G1/ PRRG1/ PRGP1 antibody for FACS & in-vivo assay
Go to PRRG1/PRRG1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1409-Ab-1/ GM-Tg-hg-MP1409-Ab-2 | Anti-Human PRRG1 monoclonal antibody | Human |
| GM-Tg-rg-MP1409-Ab-1/ GM-Tg-rg-MP1409-Ab-2 | Anti-Rat PRRG1 monoclonal antibody | Rat |
| GM-Tg-mg-MP1409-Ab-1/ GM-Tg-mg-MP1409-Ab-2 | Anti-Mouse PRRG1 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1409-Ab-1/ GM-Tg-cynog-MP1409-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PRRG1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1409-Ab-1/ GM-Tg-felg-MP1409-Ab-2 | Anti-Feline PRRG1 monoclonal antibody | Feline |
| GM-Tg-cang-MP1409-Ab-1/ GM-Tg-cang-MP1409-Ab-2 | Anti-Canine PRRG1 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1409-Ab-1/ GM-Tg-bovg-MP1409-Ab-2 | Anti-Bovine PRRG1 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1409-Ab-1/ GM-Tg-equg-MP1409-Ab-2 | Anti-Equine PRRG1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1409-Ab-1/ GM-Tg-hg-MP1409-Ab-2; GM-Tg-rg-MP1409-Ab-1/ GM-Tg-rg-MP1409-Ab-2; GM-Tg-mg-MP1409-Ab-1/ GM-Tg-mg-MP1409-Ab-2; GM-Tg-cynog-MP1409-Ab-1/ GM-Tg-cynog-MP1409-Ab-2; GM-Tg-felg-MP1409-Ab-1/ GM-Tg-felg-MP1409-Ab-2; GM-Tg-cang-MP1409-Ab-1/ GM-Tg-cang-MP1409-Ab-2; GM-Tg-bovg-MP1409-Ab-1/ GM-Tg-bovg-MP1409-Ab-2; GM-Tg-equg-MP1409-Ab-1/ GM-Tg-equg-MP1409-Ab-2 |
| Products Name | Anti-PRRG1 monoclonal antibody |
| Format | mab |
| Target Name | PRRG1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PRRG1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species ™G1/ PRRG1/ PRGP1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP004645 | human PRRG1 Lentivirus particle |
| ORF Viral Vector | pGMLP004645 | human PRRG1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000859 | mouse Prrg1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000859 | mouse Prrg1 Lentivirus particle |
Target information
| Target ID | GM-MP1409 |
| Target Name | PRRG1 |
| Gene ID | 5638,546336,363472,696938,491821,101085954,785916,100629871 |
| Gene Symbol and Synonyms | 2010007L08Rik,PRGP1,PRRG1,RGD1561320,™G1 |
| Uniprot Accession | O14668,A7Z070 |
| Uniprot Entry Name | ™G1_HUMAN,™G1_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000130962 |
| Target Classification | N/A |
The target: PRRG1, gene name: PRRG1, also named as PRGP1. This gene encodes a vitamin K-dependent, gamma-carboxyglutamic acid (Gla)-containing, single-pass transmembrane protein. This protein contains a Gla domain at the N-terminus, preceded by a propeptide sequence required for post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus is proline-rich containing PPXY and PXXP motifs found in a variety of signaling and cytoskeletal proteins. This gene is highly expressed in the spinal cord. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
