Anti-SCAM1/ SCAMP1/ SCAMP monoclonal antibody

Anti-SCAM1/ SCAMP1/ SCAMP antibody for FACS & in-vivo assay

Target products collectionGo to SCAMP1/SCAMP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1481-Ab-1/ GM-Tg-hg-MP1481-Ab-2Anti-Human SCAMP1 monoclonal antibodyHuman
GM-Tg-rg-MP1481-Ab-1/ GM-Tg-rg-MP1481-Ab-2Anti-Rat SCAMP1 monoclonal antibodyRat
GM-Tg-mg-MP1481-Ab-1/ GM-Tg-mg-MP1481-Ab-2Anti-Mouse SCAMP1 monoclonal antibodyMouse
GM-Tg-cynog-MP1481-Ab-1/ GM-Tg-cynog-MP1481-Ab-2Anti-Cynomolgus/ Rhesus macaque SCAMP1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1481-Ab-1/ GM-Tg-felg-MP1481-Ab-2Anti-Feline SCAMP1 monoclonal antibodyFeline
GM-Tg-cang-MP1481-Ab-1/ GM-Tg-cang-MP1481-Ab-2Anti-Canine SCAMP1 monoclonal antibodyCanine
GM-Tg-bovg-MP1481-Ab-1/ GM-Tg-bovg-MP1481-Ab-2Anti-Bovine SCAMP1 monoclonal antibodyBovine
GM-Tg-equg-MP1481-Ab-1/ GM-Tg-equg-MP1481-Ab-2Anti-Equine SCAMP1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1481-Ab-1/ GM-Tg-hg-MP1481-Ab-2; GM-Tg-rg-MP1481-Ab-1/ GM-Tg-rg-MP1481-Ab-2;
GM-Tg-mg-MP1481-Ab-1/ GM-Tg-mg-MP1481-Ab-2; GM-Tg-cynog-MP1481-Ab-1/ GM-Tg-cynog-MP1481-Ab-2;
GM-Tg-felg-MP1481-Ab-1/ GM-Tg-felg-MP1481-Ab-2; GM-Tg-cang-MP1481-Ab-1/ GM-Tg-cang-MP1481-Ab-2;
GM-Tg-bovg-MP1481-Ab-1/ GM-Tg-bovg-MP1481-Ab-2; GM-Tg-equg-MP1481-Ab-1/ GM-Tg-equg-MP1481-Ab-2
Products NameAnti-SCAMP1 monoclonal antibody
Formatmab
Target NameSCAMP1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SCAMP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SCAM1/ SCAMP1/ SCAMP VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP002525human SCAMP1 Lentivirus plasmid
    ORF Viral VectorvGMLP002525human SCAMP1 Lentivirus particle
    ORF Viral VectorpGMLPm004359mouse Scamp1 Lentivirus plasmid
    ORF Viral VectorvGMLPm004359mouse Scamp1 Lentivirus particle


    Target information

    Target IDGM-MP1481
    Target NameSCAMP1
    Gene ID9522,107767,29521,100424165,479172,101080863,535352,100073271
    Gene Symbol and Synonyms4930505M11Rik,SCAMP,SCAMP1,SCAMP37
    Uniprot AccessionO15126,P56603
    Uniprot Entry NameSCAM1_HUMAN,SCAM1_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000085365
    Target ClassificationN/A

    The target: SCAMP1, gene name: SCAMP1, also named as SCAMP, SCAMP37. This gene product belongs to the SCAMP family of proteins, which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that these protein family members may function at the same site during vesicular transport rather than in separate pathways. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.