Anti-COPT1/ SLC31A1/ CTR1 monoclonal antibody

Anti-COPT1/ SLC31A1/ CTR1 antibody for FACS & in-vivo assay

Target products collectionGo to SLC31A1/SLC31A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1603-Ab-1/ GM-Tg-hg-MP1603-Ab-2Anti-Human SLC31A1 monoclonal antibodyHuman
GM-Tg-rg-MP1603-Ab-1/ GM-Tg-rg-MP1603-Ab-2Anti-Rat SLC31A1 monoclonal antibodyRat
GM-Tg-mg-MP1603-Ab-1/ GM-Tg-mg-MP1603-Ab-2Anti-Mouse SLC31A1 monoclonal antibodyMouse
GM-Tg-cynog-MP1603-Ab-1/ GM-Tg-cynog-MP1603-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC31A1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1603-Ab-1/ GM-Tg-felg-MP1603-Ab-2Anti-Feline SLC31A1 monoclonal antibodyFeline
GM-Tg-cang-MP1603-Ab-1/ GM-Tg-cang-MP1603-Ab-2Anti-Canine SLC31A1 monoclonal antibodyCanine
GM-Tg-bovg-MP1603-Ab-1/ GM-Tg-bovg-MP1603-Ab-2Anti-Bovine SLC31A1 monoclonal antibodyBovine
GM-Tg-equg-MP1603-Ab-1/ GM-Tg-equg-MP1603-Ab-2Anti-Equine SLC31A1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1603-Ab-1/ GM-Tg-hg-MP1603-Ab-2; GM-Tg-rg-MP1603-Ab-1/ GM-Tg-rg-MP1603-Ab-2;
GM-Tg-mg-MP1603-Ab-1/ GM-Tg-mg-MP1603-Ab-2; GM-Tg-cynog-MP1603-Ab-1/ GM-Tg-cynog-MP1603-Ab-2;
GM-Tg-felg-MP1603-Ab-1/ GM-Tg-felg-MP1603-Ab-2; GM-Tg-cang-MP1603-Ab-1/ GM-Tg-cang-MP1603-Ab-2;
GM-Tg-bovg-MP1603-Ab-1/ GM-Tg-bovg-MP1603-Ab-2; GM-Tg-equg-MP1603-Ab-1/ GM-Tg-equg-MP1603-Ab-2
Products NameAnti-SLC31A1 monoclonal antibody
Formatmab
Target NameSLC31A1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC31A1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species COPT1/ SLC31A1/ CTR1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP003981human SLC31A1 Lentivirus particle
    ORF Viral VectorpGMLP003981human SLC31A1 Lentivirus plasmid


    Target information

    Target IDGM-MP1603
    Target NameSLC31A1
    Gene ID1317,20529,171135,706058,481678,101081582,518976,100050369
    Gene Symbol and Synonyms4930445G01Rik,COPT1,CTR1,LRRGT00200,NSCT,SLC31A1
    Uniprot AccessionO15431,Q9JK41
    Uniprot Entry NameCOPT1_HUMAN,COPT1_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseasePregnant state
    Gene EnsemblENSG00000136868
    Target ClassificationN/A

    The target: SLC31A1, gene name: SLC31A1, also named as COPT1, CTR1. The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper. [provided by RefSeq, Aug 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.