Anti-S39A3/ SLC39A3/ ZIP-3 monoclonal antibody

Anti-S39A3/ SLC39A3/ ZIP-3 antibody for FACS & in-vivo assay

Target products collectionGo to SLC39A3/SLC39A3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1617-Ab-1/ GM-Tg-hg-MP1617-Ab-2Anti-Human SLC39A3 monoclonal antibodyHuman
GM-Tg-rg-MP1617-Ab-1/ GM-Tg-rg-MP1617-Ab-2Anti-Rat SLC39A3 monoclonal antibodyRat
GM-Tg-mg-MP1617-Ab-1/ GM-Tg-mg-MP1617-Ab-2Anti-Mouse SLC39A3 monoclonal antibodyMouse
GM-Tg-cynog-MP1617-Ab-1/ GM-Tg-cynog-MP1617-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC39A3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1617-Ab-1/ GM-Tg-felg-MP1617-Ab-2Anti-Feline SLC39A3 monoclonal antibodyFeline
GM-Tg-cang-MP1617-Ab-1/ GM-Tg-cang-MP1617-Ab-2Anti-Canine SLC39A3 monoclonal antibodyCanine
GM-Tg-bovg-MP1617-Ab-1/ GM-Tg-bovg-MP1617-Ab-2Anti-Bovine SLC39A3 monoclonal antibodyBovine
GM-Tg-equg-MP1617-Ab-1/ GM-Tg-equg-MP1617-Ab-2Anti-Equine SLC39A3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1617-Ab-1/ GM-Tg-hg-MP1617-Ab-2; GM-Tg-rg-MP1617-Ab-1/ GM-Tg-rg-MP1617-Ab-2;
GM-Tg-mg-MP1617-Ab-1/ GM-Tg-mg-MP1617-Ab-2; GM-Tg-cynog-MP1617-Ab-1/ GM-Tg-cynog-MP1617-Ab-2;
GM-Tg-felg-MP1617-Ab-1/ GM-Tg-felg-MP1617-Ab-2; GM-Tg-cang-MP1617-Ab-1/ GM-Tg-cang-MP1617-Ab-2;
GM-Tg-bovg-MP1617-Ab-1/ GM-Tg-bovg-MP1617-Ab-2; GM-Tg-equg-MP1617-Ab-1/ GM-Tg-equg-MP1617-Ab-2
Products NameAnti-SLC39A3 monoclonal antibody
Formatmab
Target NameSLC39A3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC39A3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species S39A3/ SLC39A3/ ZIP-3 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP000170human SLC39A3 Lentivirus particle
    ORF Viral VectorpGMLP000170human SLC39A3 Lentivirus plasmid


    Target information

    Target IDGM-MP1617
    Target NameSLC39A3
    Gene ID29985,106947,314637,711564,612127,101088725,505294,100146878
    Gene Symbol and SynonymsSLC39A3,ZIP-3,ZIP3
    Uniprot AccessionQ9BRY0,Q5U1X7,Q5E960
    Uniprot Entry NameS39A3_HUMAN,S39A3_RAT,S39A3_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000141873
    Target ClassificationN/A

    The target: SLC39A3, gene name: SLC39A3, also named as ZIP-3, ZIP3. Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion transmembrane transport. Predicted to act upstream of or within several processes, including T cell homeostasis; chordate embryonic development; and zinc ion transport. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.