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Anti-SYT7/ IPCA-7/ IPCA7 monoclonal antibody
Anti-SYT7/ IPCA-7/ IPCA7 antibody for FACS & in-vivo assay
Go to SYT7/SYT7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1749-Ab-1/ GM-Tg-hg-MP1749-Ab-2 | Anti-Human SYT7 monoclonal antibody | Human |
| GM-Tg-rg-MP1749-Ab-1/ GM-Tg-rg-MP1749-Ab-2 | Anti-Rat SYT7 monoclonal antibody | Rat |
| GM-Tg-mg-MP1749-Ab-1/ GM-Tg-mg-MP1749-Ab-2 | Anti-Mouse SYT7 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1749-Ab-1/ GM-Tg-cynog-MP1749-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SYT7 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1749-Ab-1/ GM-Tg-felg-MP1749-Ab-2 | Anti-Feline SYT7 monoclonal antibody | Feline |
| GM-Tg-cang-MP1749-Ab-1/ GM-Tg-cang-MP1749-Ab-2 | Anti-Canine SYT7 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1749-Ab-1/ GM-Tg-bovg-MP1749-Ab-2 | Anti-Bovine SYT7 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1749-Ab-1/ GM-Tg-equg-MP1749-Ab-2 | Anti-Equine SYT7 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1749-Ab-1/ GM-Tg-hg-MP1749-Ab-2; GM-Tg-rg-MP1749-Ab-1/ GM-Tg-rg-MP1749-Ab-2; GM-Tg-mg-MP1749-Ab-1/ GM-Tg-mg-MP1749-Ab-2; GM-Tg-cynog-MP1749-Ab-1/ GM-Tg-cynog-MP1749-Ab-2; GM-Tg-felg-MP1749-Ab-1/ GM-Tg-felg-MP1749-Ab-2; GM-Tg-cang-MP1749-Ab-1/ GM-Tg-cang-MP1749-Ab-2; GM-Tg-bovg-MP1749-Ab-1/ GM-Tg-bovg-MP1749-Ab-2; GM-Tg-equg-MP1749-Ab-1/ GM-Tg-equg-MP1749-Ab-2 |
| Products Name | Anti-SYT7 monoclonal antibody |
| Format | mab |
| Target Name | SYT7 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SYT7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species SYT7/ IPCA-7/ IPCA7 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP000242 | human SYT7 Lentivirus particle |
| ORF Viral Vector | pGMLP000242 | human SYT7 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm004323 | mouse Syt7 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004323 | mouse Syt7 Lentivirus particle |
Target information
| Target ID | GM-MP1749 |
| Target Name | SYT7 |
| Gene ID | 9066,54525,59267,722368,483796,101084826,540850,100062526 |
| Gene Symbol and Synonyms | B230112P13Rik,IPCA-7,IPCA7,PCANAP7,SYT-VII,SYT7,SYTVII |
| Uniprot Accession | O43581,Q62747 |
| Uniprot Entry Name | SYT7_HUMAN,SYT7_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000011347 |
| Target Classification | N/A |
The target: SYT7, gene name: SYT7, also named as IPCA-7, IPCA7, PCANAP7, SYT-VII, SYTVII. This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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