Anti-™M88/ ™EM88 monoclonal antibody

Anti-™M88/ ™EM88 antibody for FACS & in-vivo assay

Target products collectionGo to ™EM88/™EM88 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1841-Ab-1/ GM-Tg-hg-MP1841-Ab-2Anti-Human ™EM88 monoclonal antibodyHuman
GM-Tg-rg-MP1841-Ab-1/ GM-Tg-rg-MP1841-Ab-2Anti-Rat ™EM88 monoclonal antibodyRat
GM-Tg-mg-MP1841-Ab-1/ GM-Tg-mg-MP1841-Ab-2Anti-Mouse ™EM88 monoclonal antibodyMouse
GM-Tg-cynog-MP1841-Ab-1/ GM-Tg-cynog-MP1841-Ab-2Anti-Cynomolgus/ Rhesus macaque ™EM88 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1841-Ab-1/ GM-Tg-felg-MP1841-Ab-2Anti-Feline ™EM88 monoclonal antibodyFeline
GM-Tg-cang-MP1841-Ab-1/ GM-Tg-cang-MP1841-Ab-2Anti-Canine ™EM88 monoclonal antibodyCanine
GM-Tg-bovg-MP1841-Ab-1/ GM-Tg-bovg-MP1841-Ab-2Anti-Bovine ™EM88 monoclonal antibodyBovine
GM-Tg-equg-MP1841-Ab-1/ GM-Tg-equg-MP1841-Ab-2Anti-Equine ™EM88 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1841-Ab-1/ GM-Tg-hg-MP1841-Ab-2; GM-Tg-rg-MP1841-Ab-1/ GM-Tg-rg-MP1841-Ab-2;
GM-Tg-mg-MP1841-Ab-1/ GM-Tg-mg-MP1841-Ab-2; GM-Tg-cynog-MP1841-Ab-1/ GM-Tg-cynog-MP1841-Ab-2;
GM-Tg-felg-MP1841-Ab-1/ GM-Tg-felg-MP1841-Ab-2; GM-Tg-cang-MP1841-Ab-1/ GM-Tg-cang-MP1841-Ab-2;
GM-Tg-bovg-MP1841-Ab-1/ GM-Tg-bovg-MP1841-Ab-2; GM-Tg-equg-MP1841-Ab-1/ GM-Tg-equg-MP1841-Ab-2
Products NameAnti-™EM88 monoclonal antibody
Formatmab
Target Name™EM88
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-™EM88 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ™M88/ ™EM88 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP004181human ™EM88 Lentivirus particle
    ORF Viral VectorpGMLP004181human ™EM88 Lentivirus plasmid
    ORF Viral VectorpGMLPm003514mouse Tmem88 Lentivirus plasmid
    ORF Viral VectorvGMLPm003514mouse Tmem88 Lentivirus particle


    Target information

    Target IDGM-MP1841
    Target Name™EM88
    Gene ID92162,67020,497936,716381,607946,102899448,507172,100062112
    Gene Symbol and Synonyms2600017H02Rik,RGD1561781,™EM88
    Uniprot AccessionQ6PEY1,A5D7M7
    Uniprot Entry Name™M88_HUMAN,™M88_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000167874
    Target ClassificationN/A

    The target: ™EM88, gene name: ™EM88, also named as . Predicted to enable PDZ domain binding activity. Involved in negative regulation of canonical Wnt signaling pathway; protein localization to plasma membrane; and protein stabilization. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.