Anti-TSN1/ TSPAN1/ NET1 monoclonal antibody
Anti-TSN1/ TSPAN1/ NET1 antibody for FACS & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-MP1880-Ab-1/ GM-Tg-hg-MP1880-Ab-2 | Anti-Human TSPAN1 monoclonal antibody | Human |
GM-Tg-rg-MP1880-Ab-1/ GM-Tg-rg-MP1880-Ab-2 | Anti-Rat TSPAN1 monoclonal antibody | Rat |
GM-Tg-mg-MP1880-Ab-1/ GM-Tg-mg-MP1880-Ab-2 | Anti-Mouse TSPAN1 monoclonal antibody | Mouse |
GM-Tg-cynog-MP1880-Ab-1/ GM-Tg-cynog-MP1880-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TSPAN1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-MP1880-Ab-1/ GM-Tg-felg-MP1880-Ab-2 | Anti-Feline TSPAN1 monoclonal antibody | Feline |
GM-Tg-cang-MP1880-Ab-1/ GM-Tg-cang-MP1880-Ab-2 | Anti-Canine TSPAN1 monoclonal antibody | Canine |
GM-Tg-bovg-MP1880-Ab-1/ GM-Tg-bovg-MP1880-Ab-2 | Anti-Bovine TSPAN1 monoclonal antibody | Bovine |
GM-Tg-equg-MP1880-Ab-1/ GM-Tg-equg-MP1880-Ab-2 | Anti-Equine TSPAN1 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-MP1880-Ab-1/ GM-Tg-hg-MP1880-Ab-2; GM-Tg-rg-MP1880-Ab-1/ GM-Tg-rg-MP1880-Ab-2; GM-Tg-mg-MP1880-Ab-1/ GM-Tg-mg-MP1880-Ab-2; GM-Tg-cynog-MP1880-Ab-1/ GM-Tg-cynog-MP1880-Ab-2; GM-Tg-felg-MP1880-Ab-1/ GM-Tg-felg-MP1880-Ab-2; GM-Tg-cang-MP1880-Ab-1/ GM-Tg-cang-MP1880-Ab-2; GM-Tg-bovg-MP1880-Ab-1/ GM-Tg-bovg-MP1880-Ab-2; GM-Tg-equg-MP1880-Ab-1/ GM-Tg-equg-MP1880-Ab-2 |
Products Name | Anti-TSPAN1 monoclonal antibody |
Format | mab |
Target Name | TSPAN1 |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-TSPAN1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | Products Developing | Multi-species TSN1/ TSPAN1/ NET1 VLP (virus-like particle) (Products Developing) |
ORF Viral Vector | pGMAAV000169 | human TSPAN1 AAV plasmid |
ORF Viral Vector | vGMAAV000169 | human TSPAN1 AAV particle |
ORF Viral Vector | pGMLPm000617 | mouse Tspan1 Lentivirus plasmid |
ORF Viral Vector | vGMLPm000617 | mouse Tspan1 Lentivirus particle |
Target information
Target ID | GM-MP1880 |
Target Name | TSPAN1 |
Gene ID | 10103,66805,298436,707431,100856322,101093789,506550,100064866 |
Gene Symbol and Synonyms | 9030418M05Rik,NET1,™4C,™4SF,TSPAN1 |
Uniprot Accession | O60635,Q6AYR9,Q3T0S3 |
Uniprot Entry Name | TSN1_HUMAN,TSN1_RAT,TSN1_BOVIN |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000117472 |
Target Classification | N/A |
The target: TSPAN1, gene name: TSPAN1, also named as NET1, ™4C, ™4SF. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.