Anti-VAMP5 monoclonal antibody

Anti-VAMP5 antibody for FACS & in-vivo assay

Target products collectionGo to VAMP5/VAMP5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1913-Ab-1/ GM-Tg-hg-MP1913-Ab-2Anti-Human VAMP5 monoclonal antibodyHuman
GM-Tg-rg-MP1913-Ab-1/ GM-Tg-rg-MP1913-Ab-2Anti-Rat VAMP5 monoclonal antibodyRat
GM-Tg-mg-MP1913-Ab-1/ GM-Tg-mg-MP1913-Ab-2Anti-Mouse VAMP5 monoclonal antibodyMouse
GM-Tg-cynog-MP1913-Ab-1/ GM-Tg-cynog-MP1913-Ab-2Anti-Cynomolgus/ Rhesus macaque VAMP5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1913-Ab-1/ GM-Tg-felg-MP1913-Ab-2Anti-Feline VAMP5 monoclonal antibodyFeline
GM-Tg-cang-MP1913-Ab-1/ GM-Tg-cang-MP1913-Ab-2Anti-Canine VAMP5 monoclonal antibodyCanine
GM-Tg-bovg-MP1913-Ab-1/ GM-Tg-bovg-MP1913-Ab-2Anti-Bovine VAMP5 monoclonal antibodyBovine
GM-Tg-equg-MP1913-Ab-1/ GM-Tg-equg-MP1913-Ab-2Anti-Equine VAMP5 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1913-Ab-1/ GM-Tg-hg-MP1913-Ab-2; GM-Tg-rg-MP1913-Ab-1/ GM-Tg-rg-MP1913-Ab-2;
GM-Tg-mg-MP1913-Ab-1/ GM-Tg-mg-MP1913-Ab-2; GM-Tg-cynog-MP1913-Ab-1/ GM-Tg-cynog-MP1913-Ab-2;
GM-Tg-felg-MP1913-Ab-1/ GM-Tg-felg-MP1913-Ab-2; GM-Tg-cang-MP1913-Ab-1/ GM-Tg-cang-MP1913-Ab-2;
GM-Tg-bovg-MP1913-Ab-1/ GM-Tg-bovg-MP1913-Ab-2; GM-Tg-equg-MP1913-Ab-1/ GM-Tg-equg-MP1913-Ab-2
Products NameAnti-VAMP5 monoclonal antibody
Formatmab
Target NameVAMP5
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-VAMP5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species VAMP5 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP000537human VAMP5 Lentivirus particle
    ORF Viral VectorpGMLP000537human VAMP5 Lentivirus plasmid


    Target information

    Target IDGM-MP1913
    Target NameVAMP5
    Gene ID10791,53620,89818,695471,482823,101091101,540406,100067283
    Gene Symbol and SynonymsCamp,VAMP5
    Uniprot AccessionO95183,Q9Z2J5,Q2KHY2
    Uniprot Entry NameVAMP5_HUMAN,VAMP5_RAT,VAMP5_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000168899
    Target ClassificationN/A

    The target: VAMP5, gene name: VAMP5, also named as . Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of vesicles and cell membranes. The VAMP5 gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE superfamily. This VAMP family member may participate in vesicle trafficking events that are associated with myogenesis. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.