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Anti-WNT5B monoclonal antibody
Anti-WNT5B antibody for FACS & in-vivo assay
Go to WNT5B/WNT5B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1937-Ab-1/ GM-Tg-hg-MP1937-Ab-2 | Anti-Human WNT5B monoclonal antibody | Human |
| GM-Tg-rg-MP1937-Ab-1/ GM-Tg-rg-MP1937-Ab-2 | Anti-Rat WNT5B monoclonal antibody | Rat |
| GM-Tg-mg-MP1937-Ab-1/ GM-Tg-mg-MP1937-Ab-2 | Anti-Mouse WNT5B monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1937-Ab-1/ GM-Tg-cynog-MP1937-Ab-2 | Anti-Cynomolgus/ Rhesus macaque WNT5B monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1937-Ab-1/ GM-Tg-felg-MP1937-Ab-2 | Anti-Feline WNT5B monoclonal antibody | Feline |
| GM-Tg-cang-MP1937-Ab-1/ GM-Tg-cang-MP1937-Ab-2 | Anti-Canine WNT5B monoclonal antibody | Canine |
| GM-Tg-bovg-MP1937-Ab-1/ GM-Tg-bovg-MP1937-Ab-2 | Anti-Bovine WNT5B monoclonal antibody | Bovine |
| GM-Tg-equg-MP1937-Ab-1/ GM-Tg-equg-MP1937-Ab-2 | Anti-Equine WNT5B monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1937-Ab-1/ GM-Tg-hg-MP1937-Ab-2; GM-Tg-rg-MP1937-Ab-1/ GM-Tg-rg-MP1937-Ab-2; GM-Tg-mg-MP1937-Ab-1/ GM-Tg-mg-MP1937-Ab-2; GM-Tg-cynog-MP1937-Ab-1/ GM-Tg-cynog-MP1937-Ab-2; GM-Tg-felg-MP1937-Ab-1/ GM-Tg-felg-MP1937-Ab-2; GM-Tg-cang-MP1937-Ab-1/ GM-Tg-cang-MP1937-Ab-2; GM-Tg-bovg-MP1937-Ab-1/ GM-Tg-bovg-MP1937-Ab-2; GM-Tg-equg-MP1937-Ab-1/ GM-Tg-equg-MP1937-Ab-2 |
| Products Name | Anti-WNT5B monoclonal antibody |
| Format | mab |
| Target Name | WNT5B |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-WNT5B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species WNT5B VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-MP1937-Ag-1 | wingless-type MMTV integration site family, member 5B (WNT5B) protein |
| ORF Viral Vector | vGMLP004360 | human WNT5B Lentivirus particle |
| ORF Viral Vector | pGMLP004360 | human WNT5B Lentivirus plasmid |
| ORF Viral Vector | pGMLPm005108 | mouse Wnt5b Lentivirus plasmid |
| ORF Viral Vector | vGMLPm005108 | mouse Wnt5b Lentivirus particle |
Target information
| Target ID | GM-MP1937 |
| Target Name | WNT5B |
| Gene ID | 81029,22419,282582,721685,486756,101085809,508008,100056017 |
| Gene Symbol and Synonyms | Wnt-5b,WNT5B |
| Uniprot Accession | Q9H1J7 |
| Uniprot Entry Name | WNT5B_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000111186 |
| Target Classification | N/A |
The target: WNT5B, gene name: WNT5B, also named as . The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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