Anti-ARL4C/ ARL7/ LAK monoclonal antibody

Anti-ARL4C/ ARL7/ LAK antibody for FACS & in-vivo assay

Target products collectionGo to ARL4C/ARL4C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2007-Ab-1/ GM-Tg-hg-MP2007-Ab-2Anti-Human ARL4C monoclonal antibodyHuman
GM-Tg-rg-MP2007-Ab-1/ GM-Tg-rg-MP2007-Ab-2Anti-Rat ARL4C monoclonal antibodyRat
GM-Tg-mg-MP2007-Ab-1/ GM-Tg-mg-MP2007-Ab-2Anti-Mouse ARL4C monoclonal antibodyMouse
GM-Tg-cynog-MP2007-Ab-1/ GM-Tg-cynog-MP2007-Ab-2Anti-Cynomolgus/ Rhesus macaque ARL4C monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2007-Ab-1/ GM-Tg-felg-MP2007-Ab-2Anti-Feline ARL4C monoclonal antibodyFeline
GM-Tg-cang-MP2007-Ab-1/ GM-Tg-cang-MP2007-Ab-2Anti-Canine ARL4C monoclonal antibodyCanine
GM-Tg-bovg-MP2007-Ab-1/ GM-Tg-bovg-MP2007-Ab-2Anti-Bovine ARL4C monoclonal antibodyBovine
GM-Tg-equg-MP2007-Ab-1/ GM-Tg-equg-MP2007-Ab-2Anti-Equine ARL4C monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2007-Ab-1/ GM-Tg-hg-MP2007-Ab-2; GM-Tg-rg-MP2007-Ab-1/ GM-Tg-rg-MP2007-Ab-2;
GM-Tg-mg-MP2007-Ab-1/ GM-Tg-mg-MP2007-Ab-2; GM-Tg-cynog-MP2007-Ab-1/ GM-Tg-cynog-MP2007-Ab-2;
GM-Tg-felg-MP2007-Ab-1/ GM-Tg-felg-MP2007-Ab-2; GM-Tg-cang-MP2007-Ab-1/ GM-Tg-cang-MP2007-Ab-2;
GM-Tg-bovg-MP2007-Ab-1/ GM-Tg-bovg-MP2007-Ab-2; GM-Tg-equg-MP2007-Ab-1/ GM-Tg-equg-MP2007-Ab-2
Products NameAnti-ARL4C monoclonal antibody
Formatmab
Target NameARL4C
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ARL4C benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ARL4C/ ARL7/ LAK VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP000882human ARL4C Lentivirus plasmid
    ORF Viral VectorvGMLP000882human ARL4C Lentivirus particle
    ORF Viral VectorpGMLPm000241mouse Arl4c Lentivirus plasmid
    ORF Viral VectorvGMLPm000241mouse Arl4c Lentivirus particle


    Target information

    Target IDGM-MP2007
    Target NameARL4C
    Gene ID10123,320982,103693239,715121,100685179,102899834,788039,100057460
    Gene Symbol and SynonymsA630084M22Rik,ARL4C,Arl4c-ps1,ARL7,LAK
    Uniprot AccessionP56559
    Uniprot Entry NameARL4C_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000188042
    Target ClassificationN/A

    The target: ARL4C, gene name: ARL4C, also named as ARL7, LAK. ADP-ribosylation factor-like 4C is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4C is closely similar to ARL4A and ARL4D and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in cholesterol transport. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.