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Anti-BORG4/ CDC42EP4/ CEP4 monoclonal antibody
Anti-BORG4/ CDC42EP4/ CEP4 antibody for FACS & in-vivo assay
Go to CDC42EP4/CDC42EP4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2045-Ab-1/ GM-Tg-hg-MP2045-Ab-2 | Anti-Human CDC42EP4 monoclonal antibody | Human |
| GM-Tg-rg-MP2045-Ab-1/ GM-Tg-rg-MP2045-Ab-2 | Anti-Rat CDC42EP4 monoclonal antibody | Rat |
| GM-Tg-mg-MP2045-Ab-1/ GM-Tg-mg-MP2045-Ab-2 | Anti-Mouse CDC42EP4 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2045-Ab-1/ GM-Tg-cynog-MP2045-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CDC42EP4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2045-Ab-1/ GM-Tg-felg-MP2045-Ab-2 | Anti-Feline CDC42EP4 monoclonal antibody | Feline |
| GM-Tg-cang-MP2045-Ab-1/ GM-Tg-cang-MP2045-Ab-2 | Anti-Canine CDC42EP4 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2045-Ab-1/ GM-Tg-bovg-MP2045-Ab-2 | Anti-Bovine CDC42EP4 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2045-Ab-1/ GM-Tg-equg-MP2045-Ab-2 | Anti-Equine CDC42EP4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2045-Ab-1/ GM-Tg-hg-MP2045-Ab-2; GM-Tg-rg-MP2045-Ab-1/ GM-Tg-rg-MP2045-Ab-2; GM-Tg-mg-MP2045-Ab-1/ GM-Tg-mg-MP2045-Ab-2; GM-Tg-cynog-MP2045-Ab-1/ GM-Tg-cynog-MP2045-Ab-2; GM-Tg-felg-MP2045-Ab-1/ GM-Tg-felg-MP2045-Ab-2; GM-Tg-cang-MP2045-Ab-1/ GM-Tg-cang-MP2045-Ab-2; GM-Tg-bovg-MP2045-Ab-1/ GM-Tg-bovg-MP2045-Ab-2; GM-Tg-equg-MP2045-Ab-1/ GM-Tg-equg-MP2045-Ab-2 |
| Products Name | Anti-CDC42EP4 monoclonal antibody |
| Format | mab |
| Target Name | CDC42EP4 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CDC42EP4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species BORG4/ CDC42EP4/ CEP4 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP002593 | human CDC42EP4 Lentivirus particle |
| ORF Viral Vector | pGMLP002593 | human CDC42EP4 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm001963 | mouse Cdc42ep4 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001963 | mouse Cdc42ep4 Lentivirus particle |
Target information
| Target ID | GM-MP2045 |
| Target Name | CDC42EP4 |
| Gene ID | 23580,56699,303653,696227,475907,101092563,540152,100061186 |
| Gene Symbol and Synonyms | 1500041M20Rik,BORG4,CDC42EP4,CEP4,KAIA1777 |
| Uniprot Accession | Q9H3Q1 |
| Uniprot Entry Name | BORG4_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000179604 |
| Target Classification | N/A |
The target: CDC42EP4, gene name: CDC42EP4, also named as BORG4, CEP4, KAIA1777. The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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