Anti-DUS15/ DUSP15/ C20orf57 monoclonal antibody

Anti-DUS15/ DUSP15/ C20orf57 antibody for FACS & in-vivo assay

Target products collectionGo to DUSP15/DUSP15 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2090-Ab-1/ GM-Tg-hg-MP2090-Ab-2Anti-Human DUSP15 monoclonal antibodyHuman
GM-Tg-rg-MP2090-Ab-1/ GM-Tg-rg-MP2090-Ab-2Anti-Rat DUSP15 monoclonal antibodyRat
GM-Tg-mg-MP2090-Ab-1/ GM-Tg-mg-MP2090-Ab-2Anti-Mouse DUSP15 monoclonal antibodyMouse
GM-Tg-cynog-MP2090-Ab-1/ GM-Tg-cynog-MP2090-Ab-2Anti-Cynomolgus/ Rhesus macaque DUSP15 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2090-Ab-1/ GM-Tg-felg-MP2090-Ab-2Anti-Feline DUSP15 monoclonal antibodyFeline
GM-Tg-cang-MP2090-Ab-1/ GM-Tg-cang-MP2090-Ab-2Anti-Canine DUSP15 monoclonal antibodyCanine
GM-Tg-bovg-MP2090-Ab-1/ GM-Tg-bovg-MP2090-Ab-2Anti-Bovine DUSP15 monoclonal antibodyBovine
GM-Tg-equg-MP2090-Ab-1/ GM-Tg-equg-MP2090-Ab-2Anti-Equine DUSP15 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2090-Ab-1/ GM-Tg-hg-MP2090-Ab-2; GM-Tg-rg-MP2090-Ab-1/ GM-Tg-rg-MP2090-Ab-2;
GM-Tg-mg-MP2090-Ab-1/ GM-Tg-mg-MP2090-Ab-2; GM-Tg-cynog-MP2090-Ab-1/ GM-Tg-cynog-MP2090-Ab-2;
GM-Tg-felg-MP2090-Ab-1/ GM-Tg-felg-MP2090-Ab-2; GM-Tg-cang-MP2090-Ab-1/ GM-Tg-cang-MP2090-Ab-2;
GM-Tg-bovg-MP2090-Ab-1/ GM-Tg-bovg-MP2090-Ab-2; GM-Tg-equg-MP2090-Ab-1/ GM-Tg-equg-MP2090-Ab-2
Products NameAnti-DUSP15 monoclonal antibody
Formatmab
Target NameDUSP15
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-DUSP15 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species DUS15/ DUSP15/ C20orf57 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP004826human DUSP15 Lentivirus plasmid
    ORF Viral VectorvGMLP004826human DUSP15 Lentivirus particle
    ORF Viral VectorpGMLPm001342mouse Dusp15 Lentivirus plasmid
    ORF Viral VectorvGMLPm001342mouse Dusp15 Lentivirus particle


    Target information

    Target IDGM-MP2090
    Target NameDUSP15
    Gene ID128853,252864,362238,100431027,609828,111559780,618412,100146918
    Gene Symbol and SynonymsC20orf57,DUSP15,LMW-DSP10,T-DSP10,VHY
    Uniprot AccessionQ9H1R2,B4F7B7
    Uniprot Entry NameDUS15_HUMAN,DUS15_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000149599
    Target ClassificationN/A

    The target: DUSP15, gene name: DUSP15, also named as C20orf57, VHY. The protein encoded by this gene has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. This protein may function in the differentiation of oligodendrocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.