Anti-KLF9/ BTEB/ BTEB1 monoclonal antibody

Anti-KLF9/ BTEB/ BTEB1 antibody for FACS & in-vivo assay

Target products collectionGo to KLF9/KLF9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2176-Ab-1/ GM-Tg-hg-MP2176-Ab-2Anti-Human KLF9 monoclonal antibodyHuman
GM-Tg-rg-MP2176-Ab-1/ GM-Tg-rg-MP2176-Ab-2Anti-Rat KLF9 monoclonal antibodyRat
GM-Tg-mg-MP2176-Ab-1/ GM-Tg-mg-MP2176-Ab-2Anti-Mouse KLF9 monoclonal antibodyMouse
GM-Tg-cynog-MP2176-Ab-1/ GM-Tg-cynog-MP2176-Ab-2Anti-Cynomolgus/ Rhesus macaque KLF9 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2176-Ab-1/ GM-Tg-felg-MP2176-Ab-2Anti-Feline KLF9 monoclonal antibodyFeline
GM-Tg-cang-MP2176-Ab-1/ GM-Tg-cang-MP2176-Ab-2Anti-Canine KLF9 monoclonal antibodyCanine
GM-Tg-bovg-MP2176-Ab-1/ GM-Tg-bovg-MP2176-Ab-2Anti-Bovine KLF9 monoclonal antibodyBovine
GM-Tg-equg-MP2176-Ab-1/ GM-Tg-equg-MP2176-Ab-2Anti-Equine KLF9 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2176-Ab-1/ GM-Tg-hg-MP2176-Ab-2; GM-Tg-rg-MP2176-Ab-1/ GM-Tg-rg-MP2176-Ab-2;
GM-Tg-mg-MP2176-Ab-1/ GM-Tg-mg-MP2176-Ab-2; GM-Tg-cynog-MP2176-Ab-1/ GM-Tg-cynog-MP2176-Ab-2;
GM-Tg-felg-MP2176-Ab-1/ GM-Tg-felg-MP2176-Ab-2; GM-Tg-cang-MP2176-Ab-1/ GM-Tg-cang-MP2176-Ab-2;
GM-Tg-bovg-MP2176-Ab-1/ GM-Tg-bovg-MP2176-Ab-2; GM-Tg-equg-MP2176-Ab-1/ GM-Tg-equg-MP2176-Ab-2
Products NameAnti-KLF9 monoclonal antibody
Formatmab
Target NameKLF9
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-KLF9 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species KLF9/ BTEB/ BTEB1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP001959human KLF9 Lentivirus particle
    ORF Viral VectorpGMLP001959human KLF9 Lentivirus plasmid
    ORF Viral VectorpGMLPm000990mouse Klf9 Lentivirus plasmid
    ORF Viral VectorvGMLPm000990mouse Klf9 Lentivirus particle


    Target information

    Target IDGM-MP2176
    Target NameKLF9
    Gene ID687,16601,117560,700585,484172,101090808,539139,100050300
    Gene Symbol and Synonyms2310051E17Rik,BTEB,BTEB-1,BTEB1,Gm9971,KLF9
    Uniprot AccessionQ13886,Q01713
    Uniprot Entry NameKLF9_HUMAN,KLF9_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000119138
    Target ClassificationN/A

    The target: KLF9, gene name: KLF9, also named as BTEB, BTEB1. The protein encoded by this gene is a transcription factor that binds to GC box elements located in the promoter. Binding of the encoded protein to a single GC box inhibits mRNA expression while binding to tandemly repeated GC box elements activates transcription. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.