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Anti-RAD/ RRAD/ RAD1 monoclonal antibody
Anti-RAD/ RRAD/ RAD1 antibody for FACS & in-vivo assay
Go to RRAD/RRAD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2312-Ab-1/ GM-Tg-hg-MP2312-Ab-2 | Anti-Human RRAD monoclonal antibody | Human |
| GM-Tg-rg-MP2312-Ab-1/ GM-Tg-rg-MP2312-Ab-2 | Anti-Rat RRAD monoclonal antibody | Rat |
| GM-Tg-mg-MP2312-Ab-1/ GM-Tg-mg-MP2312-Ab-2 | Anti-Mouse RRAD monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2312-Ab-1/ GM-Tg-cynog-MP2312-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RRAD monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2312-Ab-1/ GM-Tg-felg-MP2312-Ab-2 | Anti-Feline RRAD monoclonal antibody | Feline |
| GM-Tg-cang-MP2312-Ab-1/ GM-Tg-cang-MP2312-Ab-2 | Anti-Canine RRAD monoclonal antibody | Canine |
| GM-Tg-bovg-MP2312-Ab-1/ GM-Tg-bovg-MP2312-Ab-2 | Anti-Bovine RRAD monoclonal antibody | Bovine |
| GM-Tg-equg-MP2312-Ab-1/ GM-Tg-equg-MP2312-Ab-2 | Anti-Equine RRAD monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2312-Ab-1/ GM-Tg-hg-MP2312-Ab-2; GM-Tg-rg-MP2312-Ab-1/ GM-Tg-rg-MP2312-Ab-2; GM-Tg-mg-MP2312-Ab-1/ GM-Tg-mg-MP2312-Ab-2; GM-Tg-cynog-MP2312-Ab-1/ GM-Tg-cynog-MP2312-Ab-2; GM-Tg-felg-MP2312-Ab-1/ GM-Tg-felg-MP2312-Ab-2; GM-Tg-cang-MP2312-Ab-1/ GM-Tg-cang-MP2312-Ab-2; GM-Tg-bovg-MP2312-Ab-1/ GM-Tg-bovg-MP2312-Ab-2; GM-Tg-equg-MP2312-Ab-1/ GM-Tg-equg-MP2312-Ab-2 |
| Products Name | Anti-RRAD monoclonal antibody |
| Format | mab |
| Target Name | RRAD |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-RRAD benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species RAD/ RRAD/ RAD1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP005125 | human RRAD Lentivirus plasmid |
| ORF Viral Vector | vGMLP005125 | human RRAD Lentivirus particle |
| ORF Viral Vector | pGMLPm000842 | mouse Rrad Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000842 | mouse Rrad Lentivirus particle |
Target information
| Target ID | GM-MP2312 |
| Target Name | RRAD |
| Gene ID | 6236,56437,83521,695086,611304,101087028,505165,100065651 |
| Gene Symbol and Synonyms | RAD,RAD1,REM3,RRAD |
| Uniprot Accession | P55042,P55043 |
| Uniprot Entry Name | RAD_HUMAN,RAD_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000166592 |
| Target Classification | N/A |
The target: RRAD, gene name: RRAD, also named as RAD, RAD1, REM3. Predicted to enable GTP binding activity and calcium channel regulator activity. Predicted to be involved in small GTPase mediated signal transduction. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Implicated in type 2 diabetes mellitus. Biomarker of congestive heart failure. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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