Anti-S10AG/ S100A16/ AAG13 monoclonal antibody
Anti-S10AG/ S100A16/ AAG13 antibody for FACS & in-vivo assay
Go to S100A16/S100A16 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-MP2315-Ab-1/ GM-Tg-hg-MP2315-Ab-2 | Anti-Human S100A16 monoclonal antibody | Human |
GM-Tg-rg-MP2315-Ab-1/ GM-Tg-rg-MP2315-Ab-2 | Anti-Rat S100A16 monoclonal antibody | Rat |
GM-Tg-mg-MP2315-Ab-1/ GM-Tg-mg-MP2315-Ab-2 | Anti-Mouse S100A16 monoclonal antibody | Mouse |
GM-Tg-cynog-MP2315-Ab-1/ GM-Tg-cynog-MP2315-Ab-2 | Anti-Cynomolgus/ Rhesus macaque S100A16 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-MP2315-Ab-1/ GM-Tg-felg-MP2315-Ab-2 | Anti-Feline S100A16 monoclonal antibody | Feline |
GM-Tg-cang-MP2315-Ab-1/ GM-Tg-cang-MP2315-Ab-2 | Anti-Canine S100A16 monoclonal antibody | Canine |
GM-Tg-bovg-MP2315-Ab-1/ GM-Tg-bovg-MP2315-Ab-2 | Anti-Bovine S100A16 monoclonal antibody | Bovine |
GM-Tg-equg-MP2315-Ab-1/ GM-Tg-equg-MP2315-Ab-2 | Anti-Equine S100A16 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-MP2315-Ab-1/ GM-Tg-hg-MP2315-Ab-2; GM-Tg-rg-MP2315-Ab-1/ GM-Tg-rg-MP2315-Ab-2; GM-Tg-mg-MP2315-Ab-1/ GM-Tg-mg-MP2315-Ab-2; GM-Tg-cynog-MP2315-Ab-1/ GM-Tg-cynog-MP2315-Ab-2; GM-Tg-felg-MP2315-Ab-1/ GM-Tg-felg-MP2315-Ab-2; GM-Tg-cang-MP2315-Ab-1/ GM-Tg-cang-MP2315-Ab-2; GM-Tg-bovg-MP2315-Ab-1/ GM-Tg-bovg-MP2315-Ab-2; GM-Tg-equg-MP2315-Ab-1/ GM-Tg-equg-MP2315-Ab-2 |
Products Name | Anti-S100A16 monoclonal antibody |
Format | mab |
Target Name | S100A16 |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-S100A16 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | Products Developing | Multi-species S10AG/ S100A16/ AAG13 VLP (virus-like particle) (Products Developing) |
ORF Viral Vector | pGMLP000394 | human S100A16 Lentivirus plasmid |
ORF Viral Vector | vGMLP000394 | human S100A16 Lentivirus particle |
ORF Viral Vector | pGMLPm000608 | mouse S100a16 Lentivirus plasmid |
ORF Viral Vector | vGMLPm000608 | mouse S100a16 Lentivirus particle |
Target information
Target ID | GM-MP2315 |
Target Name | S100A16 |
Gene ID | 140576,67860,361991,713638,490458,101082624,505679,100056268 |
Gene Symbol and Synonyms | 2300002L21Rik,AAG13,DT1P1A7,S100A16,S100F |
Uniprot Accession | Q96FQ6,Q0VCM0 |
Uniprot Entry Name | S10AG_HUMAN,S10AG_BOVIN |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000188643 |
Target Classification | N/A |
The target: S100A16, gene name: S100A16, also named as AAG13, DT1P1A7, S100F. Enables calcium ion binding activity and protein homodimerization activity. Predicted to act upstream of or within response to calcium ion. Located in several cellular components, including cytosol; extracellular space; and nucleolus. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.