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Anti-TES/ TESSS-2 monoclonal antibody
Anti-TES/ TESSS-2 antibody for FACS & in-vivo assay
Go to TES/TES products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2352-Ab-1/ GM-Tg-hg-MP2352-Ab-2 | Anti-Human TES monoclonal antibody | Human |
| GM-Tg-rg-MP2352-Ab-1/ GM-Tg-rg-MP2352-Ab-2 | Anti-Rat TES monoclonal antibody | Rat |
| GM-Tg-mg-MP2352-Ab-1/ GM-Tg-mg-MP2352-Ab-2 | Anti-Mouse TES monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2352-Ab-1/ GM-Tg-cynog-MP2352-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TES monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2352-Ab-1/ GM-Tg-felg-MP2352-Ab-2 | Anti-Feline TES monoclonal antibody | Feline |
| GM-Tg-cang-MP2352-Ab-1/ GM-Tg-cang-MP2352-Ab-2 | Anti-Canine TES monoclonal antibody | Canine |
| GM-Tg-bovg-MP2352-Ab-1/ GM-Tg-bovg-MP2352-Ab-2 | Anti-Bovine TES monoclonal antibody | Bovine |
| GM-Tg-equg-MP2352-Ab-1/ GM-Tg-equg-MP2352-Ab-2 | Anti-Equine TES monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2352-Ab-1/ GM-Tg-hg-MP2352-Ab-2; GM-Tg-rg-MP2352-Ab-1/ GM-Tg-rg-MP2352-Ab-2; GM-Tg-mg-MP2352-Ab-1/ GM-Tg-mg-MP2352-Ab-2; GM-Tg-cynog-MP2352-Ab-1/ GM-Tg-cynog-MP2352-Ab-2; GM-Tg-felg-MP2352-Ab-1/ GM-Tg-felg-MP2352-Ab-2; GM-Tg-cang-MP2352-Ab-1/ GM-Tg-cang-MP2352-Ab-2; GM-Tg-bovg-MP2352-Ab-1/ GM-Tg-bovg-MP2352-Ab-2; GM-Tg-equg-MP2352-Ab-1/ GM-Tg-equg-MP2352-Ab-2 |
| Products Name | Anti-TES monoclonal antibody |
| Format | mab |
| Target Name | TES |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-TES benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species TES/ TESSS-2 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP005111 | human TES Lentivirus particle |
| ORF Viral Vector | vGMLV000115 | human TES Lentivirus particle |
| ORF Viral Vector | pGMLP005111 | human TES Lentivirus plasmid |
| ORF Viral Vector | pGMLV000115 | human TES Lentivirus plasmid |
| ORF Viral Vector | pGMLPm003964 | mouse Tes Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003964 | mouse Tes Lentivirus particle |
Target information
| Target ID | GM-MP2352 |
| Target Name | TES |
| Gene ID | 26136,21753,500040,706879,475293,100137197,534965,100071093 |
| Gene Symbol and Synonyms | D6Ertd352e,TES,Tes1,Tes2,TESS,TESS-2,Testin,testin2 |
| Uniprot Accession | Q9UGI8,Q2LAP6,A0M8U6,A0M8S5,Q2YDE9,Q2QLB2 |
| Uniprot Entry Name | TES_HUMAN,TES_RAT,TES_FELCA,TES_CANLF,TES_BOVIN,TES_HORSE |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000135269 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: TES, gene name: TES, also named as TESSS-2, TES. Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.[provided by RefSeq, Mar 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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