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Anti-RL40/ UBA52/ CEP52 monoclonal antibody
Anti-RL40/ UBA52/ CEP52 antibody for FACS & in-vivo assay
Go to UBA52/UBA52 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2368-Ab-1/ GM-Tg-hg-MP2368-Ab-2 | Anti-Human UBA52 monoclonal antibody | Human |
| GM-Tg-rg-MP2368-Ab-1/ GM-Tg-rg-MP2368-Ab-2 | Anti-Rat UBA52 monoclonal antibody | Rat |
| GM-Tg-mg-MP2368-Ab-1/ GM-Tg-mg-MP2368-Ab-2 | Anti-Mouse UBA52 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2368-Ab-1/ GM-Tg-cynog-MP2368-Ab-2 | Anti-Cynomolgus/ Rhesus macaque UBA52 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2368-Ab-1/ GM-Tg-felg-MP2368-Ab-2 | Anti-Feline UBA52 monoclonal antibody | Feline |
| GM-Tg-cang-MP2368-Ab-1/ GM-Tg-cang-MP2368-Ab-2 | Anti-Canine UBA52 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2368-Ab-1/ GM-Tg-bovg-MP2368-Ab-2 | Anti-Bovine UBA52 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2368-Ab-1/ GM-Tg-equg-MP2368-Ab-2 | Anti-Equine UBA52 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2368-Ab-1/ GM-Tg-hg-MP2368-Ab-2; GM-Tg-rg-MP2368-Ab-1/ GM-Tg-rg-MP2368-Ab-2; GM-Tg-mg-MP2368-Ab-1/ GM-Tg-mg-MP2368-Ab-2; GM-Tg-cynog-MP2368-Ab-1/ GM-Tg-cynog-MP2368-Ab-2; GM-Tg-felg-MP2368-Ab-1/ GM-Tg-felg-MP2368-Ab-2; GM-Tg-cang-MP2368-Ab-1/ GM-Tg-cang-MP2368-Ab-2; GM-Tg-bovg-MP2368-Ab-1/ GM-Tg-bovg-MP2368-Ab-2; GM-Tg-equg-MP2368-Ab-1/ GM-Tg-equg-MP2368-Ab-2 |
| Products Name | Anti-UBA52 monoclonal antibody |
| Format | mab |
| Target Name | UBA52 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-UBA52 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species RL40/ UBA52/ CEP52 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP003398 | human UBA52 Lentivirus particle |
| ORF Viral Vector | pGMLP003398 | human UBA52 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000660 | mouse Uba52 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000660 | mouse Uba52 Lentivirus particle |
Target information
| Target ID | GM-MP2368 |
| Target Name | UBA52 |
| Gene ID | 7311,22186,64156,720243,403722,100144608,615199,100071005 |
| Gene Symbol and Synonyms | CEP52,D8Ertd21e,Gm1863,HUBCEP52,L40,RPL40,Rps27a,UB-RPL40,UBA52,Ubb,Ubc,UBCEP2 |
| Uniprot Accession | P62987,P62986,P63050,P63052,P63048 |
| Uniprot Entry Name | RL40_HUMAN,RL40_RAT,RL40_FELCA,RL40_CANLF,RL40_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Lung Cancer, Diabetic Nephropathy |
| Gene Ensembl | ENSG00000221983 |
| Target Classification | N/A |
The target: UBA52, gene name: UBA52, also named as CEP52, HUBCEP52, L40, RPL40. Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein (CEP). Multiple processed pseudogenes derived from this gene are present in the genome. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
