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Anti-MSRA/ PMSR monoclonal antibody
Anti-MSRA/ PMSR antibody for FACS & in-vivo assay
Go to MSRA/MSRA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2600-Ab-1/ GM-Tg-hg-MP2600-Ab-2 | Anti-Human MSRA monoclonal antibody | Human |
| GM-Tg-rg-MP2600-Ab-1/ GM-Tg-rg-MP2600-Ab-2 | Anti-Rat MSRA monoclonal antibody | Rat |
| GM-Tg-mg-MP2600-Ab-1/ GM-Tg-mg-MP2600-Ab-2 | Anti-Mouse MSRA monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2600-Ab-1/ GM-Tg-cynog-MP2600-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MSRA monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2600-Ab-1/ GM-Tg-felg-MP2600-Ab-2 | Anti-Feline MSRA monoclonal antibody | Feline |
| GM-Tg-cang-MP2600-Ab-1/ GM-Tg-cang-MP2600-Ab-2 | Anti-Canine MSRA monoclonal antibody | Canine |
| GM-Tg-bovg-MP2600-Ab-1/ GM-Tg-bovg-MP2600-Ab-2 | Anti-Bovine MSRA monoclonal antibody | Bovine |
| GM-Tg-equg-MP2600-Ab-1/ GM-Tg-equg-MP2600-Ab-2 | Anti-Equine MSRA monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2600-Ab-1/ GM-Tg-hg-MP2600-Ab-2; GM-Tg-rg-MP2600-Ab-1/ GM-Tg-rg-MP2600-Ab-2; GM-Tg-mg-MP2600-Ab-1/ GM-Tg-mg-MP2600-Ab-2; GM-Tg-cynog-MP2600-Ab-1/ GM-Tg-cynog-MP2600-Ab-2; GM-Tg-felg-MP2600-Ab-1/ GM-Tg-felg-MP2600-Ab-2; GM-Tg-cang-MP2600-Ab-1/ GM-Tg-cang-MP2600-Ab-2; GM-Tg-bovg-MP2600-Ab-1/ GM-Tg-bovg-MP2600-Ab-2; GM-Tg-equg-MP2600-Ab-1/ GM-Tg-equg-MP2600-Ab-2 |
| Products Name | Anti-MSRA monoclonal antibody |
| Format | mab |
| Target Name | MSRA |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MSRA benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species MSRA/ PMSR VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP000029 | human MSRA Lentivirus plasmid |
| ORF Viral Vector | vGMLP000029 | human MSRA Lentivirus particle |
| ORF Viral Vector | pGMLPm000417 | mouse Msra Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000417 | mouse Msra Lentivirus particle |
Target information
| Target ID | GM-MP2600 |
| Target Name | MSRA |
| Gene ID | 4482,110265,29447,698628,608103,101082232,281312,100061773 |
| Gene Symbol and Synonyms | 2310045J23Rik,6530413P12Rik,MSR-A,MSRA,PMSR |
| Uniprot Accession | Q9UJ68,Q923M1,P54149 |
| Uniprot Entry Name | MSRA_HUMAN,MSRA_RAT,MSRA_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Prostate Cancer |
| Gene Ensembl | ENSG00000175806 |
| Target Classification | N/A |
The target: MSRA, gene name: MSRA, also named as PMSR. This gene encodes a ubiquitous and highly conserved protein that carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. The protein functions in the repair of oxidatively damaged proteins to restore biological activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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