Anti-MSRA/ PMSR monoclonal antibody

Anti-MSRA/ PMSR antibody for FACS & in-vivo assay

Target products collectionGo to MSRA/MSRA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2600-Ab-1/ GM-Tg-hg-MP2600-Ab-2Anti-Human MSRA monoclonal antibodyHuman
GM-Tg-rg-MP2600-Ab-1/ GM-Tg-rg-MP2600-Ab-2Anti-Rat MSRA monoclonal antibodyRat
GM-Tg-mg-MP2600-Ab-1/ GM-Tg-mg-MP2600-Ab-2Anti-Mouse MSRA monoclonal antibodyMouse
GM-Tg-cynog-MP2600-Ab-1/ GM-Tg-cynog-MP2600-Ab-2Anti-Cynomolgus/ Rhesus macaque MSRA monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2600-Ab-1/ GM-Tg-felg-MP2600-Ab-2Anti-Feline MSRA monoclonal antibodyFeline
GM-Tg-cang-MP2600-Ab-1/ GM-Tg-cang-MP2600-Ab-2Anti-Canine MSRA monoclonal antibodyCanine
GM-Tg-bovg-MP2600-Ab-1/ GM-Tg-bovg-MP2600-Ab-2Anti-Bovine MSRA monoclonal antibodyBovine
GM-Tg-equg-MP2600-Ab-1/ GM-Tg-equg-MP2600-Ab-2Anti-Equine MSRA monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2600-Ab-1/ GM-Tg-hg-MP2600-Ab-2; GM-Tg-rg-MP2600-Ab-1/ GM-Tg-rg-MP2600-Ab-2;
GM-Tg-mg-MP2600-Ab-1/ GM-Tg-mg-MP2600-Ab-2; GM-Tg-cynog-MP2600-Ab-1/ GM-Tg-cynog-MP2600-Ab-2;
GM-Tg-felg-MP2600-Ab-1/ GM-Tg-felg-MP2600-Ab-2; GM-Tg-cang-MP2600-Ab-1/ GM-Tg-cang-MP2600-Ab-2;
GM-Tg-bovg-MP2600-Ab-1/ GM-Tg-bovg-MP2600-Ab-2; GM-Tg-equg-MP2600-Ab-1/ GM-Tg-equg-MP2600-Ab-2
Products NameAnti-MSRA monoclonal antibody
Formatmab
Target NameMSRA
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MSRA benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MSRA/ PMSR VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP000029human MSRA Lentivirus plasmid
    ORF Viral VectorvGMLP000029human MSRA Lentivirus particle
    ORF Viral VectorpGMLPm000417mouse Msra Lentivirus plasmid
    ORF Viral VectorvGMLPm000417mouse Msra Lentivirus particle


    Target information

    Target IDGM-MP2600
    Target NameMSRA
    Gene ID4482,110265,29447,698628,608103,101082232,281312,100061773
    Gene Symbol and Synonyms2310045J23Rik,6530413P12Rik,MSR-A,MSRA,PMSR
    Uniprot AccessionQ9UJ68,Q923M1,P54149
    Uniprot Entry NameMSRA_HUMAN,MSRA_RAT,MSRA_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseProstate Cancer
    Gene EnsemblENSG00000175806
    Target ClassificationN/A

    The target: MSRA, gene name: MSRA, also named as PMSR. This gene encodes a ubiquitous and highly conserved protein that carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. The protein functions in the repair of oxidatively damaged proteins to restore biological activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.