Anti-ERP29/ C12orf8/ ERp28 functional antibody

Anti-ERP29/ C12orf8/ ERp28 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to ERP29/ERP29 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE0187-Ab-1/ GM-Tg-hg-SE0187-Ab-2Anti-Human ERP29 monoclonal antibodyHuman
GM-Tg-rg-SE0187-Ab-1/ GM-Tg-rg-SE0187-Ab-2Anti-Rat ERP29 monoclonal antibodyRat
GM-Tg-mg-SE0187-Ab-1/ GM-Tg-mg-SE0187-Ab-2Anti-Mouse ERP29 monoclonal antibodyMouse
GM-Tg-cynog-SE0187-Ab-1/ GM-Tg-cynog-SE0187-Ab-2Anti-Cynomolgus/ Rhesus macaque ERP29 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE0187-Ab-1/ GM-Tg-felg-SE0187-Ab-2Anti-Feline ERP29 monoclonal antibodyFeline
GM-Tg-cang-SE0187-Ab-1/ GM-Tg-cang-SE0187-Ab-2Anti-Canine ERP29 monoclonal antibodyCanine
GM-Tg-bovg-SE0187-Ab-1/ GM-Tg-bovg-SE0187-Ab-2Anti-Bovine ERP29 monoclonal antibodyBovine
GM-Tg-equg-SE0187-Ab-1/ GM-Tg-equg-SE0187-Ab-2Anti-Equine ERP29 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE0187-Ab-1/ GM-Tg-hg-SE0187-Ab-2; GM-Tg-rg-SE0187-Ab-1/ GM-Tg-rg-SE0187-Ab-2;
GM-Tg-mg-SE0187-Ab-1/ GM-Tg-mg-SE0187-Ab-2; GM-Tg-cynog-SE0187-Ab-1/ GM-Tg-cynog-SE0187-Ab-2;
GM-Tg-felg-SE0187-Ab-1/ GM-Tg-felg-SE0187-Ab-2; GM-Tg-cang-SE0187-Ab-1/ GM-Tg-cang-SE0187-Ab-2;
GM-Tg-bovg-SE0187-Ab-1/ GM-Tg-bovg-SE0187-Ab-2; GM-Tg-equg-SE0187-Ab-1/ GM-Tg-equg-SE0187-Ab-2
Products NameAnti-ERP29 monoclonal antibody
Formatmab
Target NameERP29
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-ERP29 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE0187-Ag-1Recombinant multi-species ERP29/ C12orf8/ ERp28 protein
    ORF Viral VectorpGMLV000183human ERP29 Lentivirus plasmid
    ORF Viral VectorvGMLV000183human ERP29 Lentivirus particle
    ORF Viral VectorpGMLPm000557mouse Erp29 Lentivirus plasmid
    ORF Viral VectorvGMLPm000557mouse Erp29 Lentivirus particle


    Target information

    Target IDGM-SE0187
    Target NameERP29
    Gene ID10961,67397,117030,711484,477482,101083974,613357,100057258
    Gene Symbol and Synonyms1200015M03Rik,2810446M09Rik,C12orf8,ERp28,ERP29,ERp31,HEL-S-107,PDI-DB,PDIA9
    Uniprot AccessionP30040,P52555,P81623
    Uniprot Entry NameERP29_HUMAN,ERP29_RAT,ERP29_BOVIN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    Category
    DiseaseN/A
    Gene EnsemblENSG00000089248
    Target ClassificationN/A

    The target: ERP29, gene name: ERP29, also named as C12orf8, ERp28, ERp31, HEL-S-107, PDI-DB, PDIA9. This gene encodes a protein which localizes to the lumen of the endoplasmic reticulum (ER). It is a member of the protein disulfide isomerase (PDI) protein family but lacks an active thioredoxin motif, suggesting that this protein does not function as a disulfide isomerase. The canonical protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.