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Anti-SG11B/ SPAG11B/ EDDM2B functional antibody
Anti-SG11B/ SPAG11B/ EDDM2B functional antibody for cell culture, ELISA & in-vivo assay
Go to SPAG11B/SPAG11B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0624-Ab-1/ GM-Tg-hg-SE0624-Ab-2 | Anti-Human SPAG11B monoclonal antibody | Human |
| GM-Tg-rg-SE0624-Ab-1/ GM-Tg-rg-SE0624-Ab-2 | Anti-Rat SPAG11B monoclonal antibody | Rat |
| GM-Tg-mg-SE0624-Ab-1/ GM-Tg-mg-SE0624-Ab-2 | Anti-Mouse SPAG11B monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0624-Ab-1/ GM-Tg-cynog-SE0624-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SPAG11B monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0624-Ab-1/ GM-Tg-felg-SE0624-Ab-2 | Anti-Feline SPAG11B monoclonal antibody | Feline |
| GM-Tg-cang-SE0624-Ab-1/ GM-Tg-cang-SE0624-Ab-2 | Anti-Canine SPAG11B monoclonal antibody | Canine |
| GM-Tg-bovg-SE0624-Ab-1/ GM-Tg-bovg-SE0624-Ab-2 | Anti-Bovine SPAG11B monoclonal antibody | Bovine |
| GM-Tg-equg-SE0624-Ab-1/ GM-Tg-equg-SE0624-Ab-2 | Anti-Equine SPAG11B monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0624-Ab-1/ GM-Tg-hg-SE0624-Ab-2; GM-Tg-rg-SE0624-Ab-1/ GM-Tg-rg-SE0624-Ab-2; GM-Tg-mg-SE0624-Ab-1/ GM-Tg-mg-SE0624-Ab-2; GM-Tg-cynog-SE0624-Ab-1/ GM-Tg-cynog-SE0624-Ab-2; GM-Tg-felg-SE0624-Ab-1/ GM-Tg-felg-SE0624-Ab-2; GM-Tg-cang-SE0624-Ab-1/ GM-Tg-cang-SE0624-Ab-2; GM-Tg-bovg-SE0624-Ab-1/ GM-Tg-bovg-SE0624-Ab-2; GM-Tg-equg-SE0624-Ab-1/ GM-Tg-equg-SE0624-Ab-2 |
| Products Name | Anti-SPAG11B monoclonal antibody |
| Format | mab |
| Target Name | SPAG11B |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SPAG11B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0624-Ag-1 | Recombinant multi-species SG11B/ SPAG11B/ EDDM2B protein |
| ORF Viral Vector | pGMLP004899 | human SPAG11B Lentivirus plasmid |
| ORF Viral Vector | vGMLP004899 | human SPAG11B Lentivirus particle |
Target information
| Target ID | GM-SE0624 |
| Target Name | SPAG11B |
| Gene ID | 10407,641436 |
| Gene Symbol and Synonyms | EDDM2B,EP2,EP2C,EP2D,EP2L,HE2,HE2C,SPAG11,SPAG11A,SPAG11B |
| Uniprot Accession | Q08648 |
| Uniprot Entry Name | SG11B_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000164871 |
| Target Classification | N/A |
The target: SPAG11B, gene name: SPAG11B, also named as EDDM2B, EP2, EP2C, EP2D, HE2, HE2C, SPAG11, SPAG11A. This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides. The gene is located on chromosome 8p23 near the defensin gene cluster. Alternative splicing of this gene results in seven transcript variants encoding different isoforms. Two different N-terminal and five different C-terminal protein sequences are encoded by the splice variants. Two additional variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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