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Anti-EPPI/ EPPIN/ CT71 functional antibody
Anti-EPPI/ EPPIN/ CT71 functional antibody for cell culture, ELISA & in-vivo assay
Go to EPPIN/EPPIN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0905-Ab-1/ GM-Tg-hg-SE0905-Ab-2 | Anti-Human EPPIN monoclonal antibody | Human |
| GM-Tg-rg-SE0905-Ab-1/ GM-Tg-rg-SE0905-Ab-2 | Anti-Rat EPPIN monoclonal antibody | Rat |
| GM-Tg-mg-SE0905-Ab-1/ GM-Tg-mg-SE0905-Ab-2 | Anti-Mouse EPPIN monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0905-Ab-1/ GM-Tg-cynog-SE0905-Ab-2 | Anti-Cynomolgus/ Rhesus macaque EPPIN monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0905-Ab-1/ GM-Tg-felg-SE0905-Ab-2 | Anti-Feline EPPIN monoclonal antibody | Feline |
| GM-Tg-cang-SE0905-Ab-1/ GM-Tg-cang-SE0905-Ab-2 | Anti-Canine EPPIN monoclonal antibody | Canine |
| GM-Tg-bovg-SE0905-Ab-1/ GM-Tg-bovg-SE0905-Ab-2 | Anti-Bovine EPPIN monoclonal antibody | Bovine |
| GM-Tg-equg-SE0905-Ab-1/ GM-Tg-equg-SE0905-Ab-2 | Anti-Equine EPPIN monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0905-Ab-1/ GM-Tg-hg-SE0905-Ab-2; GM-Tg-rg-SE0905-Ab-1/ GM-Tg-rg-SE0905-Ab-2; GM-Tg-mg-SE0905-Ab-1/ GM-Tg-mg-SE0905-Ab-2; GM-Tg-cynog-SE0905-Ab-1/ GM-Tg-cynog-SE0905-Ab-2; GM-Tg-felg-SE0905-Ab-1/ GM-Tg-felg-SE0905-Ab-2; GM-Tg-cang-SE0905-Ab-1/ GM-Tg-cang-SE0905-Ab-2; GM-Tg-bovg-SE0905-Ab-1/ GM-Tg-bovg-SE0905-Ab-2; GM-Tg-equg-SE0905-Ab-1/ GM-Tg-equg-SE0905-Ab-2 |
| Products Name | Anti-EPPIN monoclonal antibody |
| Format | mab |
| Target Name | EPPIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-EPPIN benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0905-Ag-1 | Recombinant multi-species EPPI/ EPPIN/ CT71 protein |
| ORF Viral Vector | pGMLP004546 | human EPPIN Lentivirus plasmid |
| ORF Viral Vector | vGMLP004546 | human EPPIN Lentivirus particle |
| ORF Viral Vector | pGMLPm000297 | mouse Eppin Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000297 | mouse Eppin Lentivirus particle |
Target information
| Target ID | GM-SE0905 |
| Target Name | EPPIN |
| Gene ID | 57119,75526 |
| Gene Symbol and Synonyms | 1700024E17Rik,CT71,CT72,dJ461P17.2,EPPIN,SPINLW1,WAP7,WFDC7 |
| Uniprot Accession | O95925 |
| Uniprot Entry Name | EPPI_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000101448 |
| Target Classification | N/A |
The target: EPPIN, gene name: EPPIN, also named as CT71, CT72, SPINLW1, WAP7, WFDC7, dJ461P17.2. This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. The protein can inhibit human sperm motility and exhibits antimicrobial activity against E. coli, and polymorphisms in this gene are associated with male infertility. Read-through transcription also exists between this gene and the downstream WFDC6 (WAP four-disulfide core domain 6) gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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