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Anti-FGF17/ FGF-13/ FGF-17 functional antibody
Anti-FGF17/ FGF-13/ FGF-17 functional antibody for cell culture, ELISA & in-vivo assay
Go to FGF17/FGF17 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0918-Ab-1/ GM-Tg-hg-SE0918-Ab-2 | Anti-Human FGF17 monoclonal antibody | Human |
| GM-Tg-rg-SE0918-Ab-1/ GM-Tg-rg-SE0918-Ab-2 | Anti-Rat FGF17 monoclonal antibody | Rat |
| GM-Tg-mg-SE0918-Ab-1/ GM-Tg-mg-SE0918-Ab-2 | Anti-Mouse FGF17 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0918-Ab-1/ GM-Tg-cynog-SE0918-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FGF17 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0918-Ab-1/ GM-Tg-felg-SE0918-Ab-2 | Anti-Feline FGF17 monoclonal antibody | Feline |
| GM-Tg-cang-SE0918-Ab-1/ GM-Tg-cang-SE0918-Ab-2 | Anti-Canine FGF17 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0918-Ab-1/ GM-Tg-bovg-SE0918-Ab-2 | Anti-Bovine FGF17 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0918-Ab-1/ GM-Tg-equg-SE0918-Ab-2 | Anti-Equine FGF17 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0918-Ab-1/ GM-Tg-hg-SE0918-Ab-2; GM-Tg-rg-SE0918-Ab-1/ GM-Tg-rg-SE0918-Ab-2; GM-Tg-mg-SE0918-Ab-1/ GM-Tg-mg-SE0918-Ab-2; GM-Tg-cynog-SE0918-Ab-1/ GM-Tg-cynog-SE0918-Ab-2; GM-Tg-felg-SE0918-Ab-1/ GM-Tg-felg-SE0918-Ab-2; GM-Tg-cang-SE0918-Ab-1/ GM-Tg-cang-SE0918-Ab-2; GM-Tg-bovg-SE0918-Ab-1/ GM-Tg-bovg-SE0918-Ab-2; GM-Tg-equg-SE0918-Ab-1/ GM-Tg-equg-SE0918-Ab-2 |
| Products Name | Anti-FGF17 monoclonal antibody |
| Format | mab |
| Target Name | FGF17 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FGF17 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0918-Ag-1 | Recombinant multi-species FGF17/ FGF-13/ FGF-17 protein |
| Cytokine | GM-Tg-g-SE0918-Ag-1 | fibroblast growth factor 17 (FGF17) protein |
| ORF Viral Vector | vGMLP000256 | human FGF17 Lentivirus particle |
| ORF Viral Vector | pGMLP000256 | human FGF17 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000371 | mouse Fgf17 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000371 | mouse Fgf17 Lentivirus particle |
Target information
| Target ID | GM-SE0918 |
| Target Name | FGF17 |
| Gene ID | 8822,14171,29368,706659,607952,101090606,100300257,100056444 |
| Gene Symbol and Synonyms | FGF-13,FGF-17,FGF17,Fgf6b,HH20 |
| Uniprot Accession | O60258,P63076 |
| Uniprot Entry Name | FGF17_HUMAN,FGF17_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Cytokine Target |
| Disease | Lung Cancer |
| Gene Ensembl | ENSG00000158815 |
| Target Classification | N/A |
The target: FGF17, gene name: FGF17, also named as FGF-13, FGF-17, HH20. This gene encodes a member of the fibroblast growth factor (FGF) family. Member of the FGF family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is expressed during embryogenesis and in the adult cerebellum and cortex and may be essential for vascular growth and normal brain development. Mutations in this gene are the cause of hypogonadotropic hypogonadism 20 with or without anosmia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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