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Anti-FGF5/ HBGF-5/ Smag-82 functional antibody
Anti-FGF5/ HBGF-5/ Smag-82 functional antibody for cell culture, ELISA & in-vivo assay
Go to FGF5/FGF5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0922-Ab-1/ GM-Tg-hg-SE0922-Ab-2 | Anti-Human FGF5 monoclonal antibody | Human |
| GM-Tg-rg-SE0922-Ab-1/ GM-Tg-rg-SE0922-Ab-2 | Anti-Rat FGF5 monoclonal antibody | Rat |
| GM-Tg-mg-SE0922-Ab-1/ GM-Tg-mg-SE0922-Ab-2 | Anti-Mouse FGF5 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0922-Ab-1/ GM-Tg-cynog-SE0922-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FGF5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0922-Ab-1/ GM-Tg-felg-SE0922-Ab-2 | Anti-Feline FGF5 monoclonal antibody | Feline |
| GM-Tg-cang-SE0922-Ab-1/ GM-Tg-cang-SE0922-Ab-2 | Anti-Canine FGF5 monoclonal antibody | Canine |
| GM-Tg-bovg-SE0922-Ab-1/ GM-Tg-bovg-SE0922-Ab-2 | Anti-Bovine FGF5 monoclonal antibody | Bovine |
| GM-Tg-equg-SE0922-Ab-1/ GM-Tg-equg-SE0922-Ab-2 | Anti-Equine FGF5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0922-Ab-1/ GM-Tg-hg-SE0922-Ab-2; GM-Tg-rg-SE0922-Ab-1/ GM-Tg-rg-SE0922-Ab-2; GM-Tg-mg-SE0922-Ab-1/ GM-Tg-mg-SE0922-Ab-2; GM-Tg-cynog-SE0922-Ab-1/ GM-Tg-cynog-SE0922-Ab-2; GM-Tg-felg-SE0922-Ab-1/ GM-Tg-felg-SE0922-Ab-2; GM-Tg-cang-SE0922-Ab-1/ GM-Tg-cang-SE0922-Ab-2; GM-Tg-bovg-SE0922-Ab-1/ GM-Tg-bovg-SE0922-Ab-2; GM-Tg-equg-SE0922-Ab-1/ GM-Tg-equg-SE0922-Ab-2 |
| Products Name | Anti-FGF5 monoclonal antibody |
| Format | mab |
| Target Name | FGF5 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FGF5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0922-Ag-1 | Recombinant multi-species FGF5/ HBGF-5/ Smag-82 protein |
| Cytokine | GM-Tg-g-SE0922-Ag-1 | fibroblast growth factor 5 (FGF5) protein |
| ORF Viral Vector | vGMLP001159 | human FGF5 Lentivirus particle |
| ORF Viral Vector | pGMLP001159 | human FGF5 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002451 | mouse Fgf5 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002451 | mouse Fgf5 Lentivirus particle |
Target information
| Target ID | GM-SE0922 |
| Target Name | FGF5 |
| Gene ID | 2250,14176,60662,695896,608459,100136904,536771,100060219 |
| Gene Symbol and Synonyms | angora,Fgf-5,Fgf3a,FGF5,go,HBGF-5,Smag-82,TCMGLY |
| Uniprot Accession | P12034,P48807,Q20FD0,M3X9S6,A0MTF4 |
| Uniprot Entry Name | FGF5_HUMAN,FGF5_RAT,FGF5_FELCA,FGF5_CANLF,FGF5_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000138675 |
| Target Classification | N/A |
The target: FGF5, gene name: FGF5, also named as HBGF-5, Smag-82, TCMGLY. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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