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Anti-INHA functional antibody
Anti-INHA functional antibody for cell culture, ELISA & in-vivo assay
Go to INHA/INHA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1032-Ab-1/ GM-Tg-hg-SE1032-Ab-2 | Anti-Human INHA monoclonal antibody | Human |
| GM-Tg-rg-SE1032-Ab-1/ GM-Tg-rg-SE1032-Ab-2 | Anti-Rat INHA monoclonal antibody | Rat |
| GM-Tg-mg-SE1032-Ab-1/ GM-Tg-mg-SE1032-Ab-2 | Anti-Mouse INHA monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1032-Ab-1/ GM-Tg-cynog-SE1032-Ab-2 | Anti-Cynomolgus/ Rhesus macaque INHA monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1032-Ab-1/ GM-Tg-felg-SE1032-Ab-2 | Anti-Feline INHA monoclonal antibody | Feline |
| GM-Tg-cang-SE1032-Ab-1/ GM-Tg-cang-SE1032-Ab-2 | Anti-Canine INHA monoclonal antibody | Canine |
| GM-Tg-bovg-SE1032-Ab-1/ GM-Tg-bovg-SE1032-Ab-2 | Anti-Bovine INHA monoclonal antibody | Bovine |
| GM-Tg-equg-SE1032-Ab-1/ GM-Tg-equg-SE1032-Ab-2 | Anti-Equine INHA monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1032-Ab-1/ GM-Tg-hg-SE1032-Ab-2; GM-Tg-rg-SE1032-Ab-1/ GM-Tg-rg-SE1032-Ab-2; GM-Tg-mg-SE1032-Ab-1/ GM-Tg-mg-SE1032-Ab-2; GM-Tg-cynog-SE1032-Ab-1/ GM-Tg-cynog-SE1032-Ab-2; GM-Tg-felg-SE1032-Ab-1/ GM-Tg-felg-SE1032-Ab-2; GM-Tg-cang-SE1032-Ab-1/ GM-Tg-cang-SE1032-Ab-2; GM-Tg-bovg-SE1032-Ab-1/ GM-Tg-bovg-SE1032-Ab-2; GM-Tg-equg-SE1032-Ab-1/ GM-Tg-equg-SE1032-Ab-2 |
| Products Name | Anti-INHA monoclonal antibody |
| Format | mab |
| Target Name | INHA |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-INHA benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1032-Ag-1 | Recombinant multi-species INHA protein |
| ORF Viral Vector | pGMLP000475 | human INHA Lentivirus plasmid |
| ORF Viral Vector | vGMLP000475 | human INHA Lentivirus particle |
| ORF Viral Vector | vGMAP000323 | Human INHA Adenovirus particle |
| ORF Viral Vector | pGMAP000323 | Human INHA Adenovirus plasmid |
| ORF Viral Vector | pGMLPm002920 | mouse Inha Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002920 | mouse Inha Lentivirus particle |
Target information
| Target ID | GM-SE1032 |
| Target Name | INHA |
| Gene ID | 3623,16322,24504,574379,488540,101098000,281254,100034077 |
| Gene Symbol and Synonyms | INHA |
| Uniprot Accession | P05111,P17490,P07994,P55101 |
| Uniprot Entry Name | INHA_HUMAN,INHA_RAT,INHA_BOVIN,INHA_HORSE |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000123999 |
| Target Classification | N/A |
The target: INHA, gene name: INHA, also named as . This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients. [provided by RefSeq, Aug 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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