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Anti-INSL3/ RLF/ RLNL functional antibody
Anti-INSL3/ RLF/ RLNL functional antibody for cell culture, ELISA & in-vivo assay
Go to INSL3/INSL3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1034-Ab-1/ GM-Tg-hg-SE1034-Ab-2 | Anti-Human INSL3 monoclonal antibody | Human |
| GM-Tg-rg-SE1034-Ab-1/ GM-Tg-rg-SE1034-Ab-2 | Anti-Rat INSL3 monoclonal antibody | Rat |
| GM-Tg-mg-SE1034-Ab-1/ GM-Tg-mg-SE1034-Ab-2 | Anti-Mouse INSL3 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1034-Ab-1/ GM-Tg-cynog-SE1034-Ab-2 | Anti-Cynomolgus/ Rhesus macaque INSL3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1034-Ab-1/ GM-Tg-felg-SE1034-Ab-2 | Anti-Feline INSL3 monoclonal antibody | Feline |
| GM-Tg-cang-SE1034-Ab-1/ GM-Tg-cang-SE1034-Ab-2 | Anti-Canine INSL3 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1034-Ab-1/ GM-Tg-bovg-SE1034-Ab-2 | Anti-Bovine INSL3 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1034-Ab-1/ GM-Tg-equg-SE1034-Ab-2 | Anti-Equine INSL3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1034-Ab-1/ GM-Tg-hg-SE1034-Ab-2; GM-Tg-rg-SE1034-Ab-1/ GM-Tg-rg-SE1034-Ab-2; GM-Tg-mg-SE1034-Ab-1/ GM-Tg-mg-SE1034-Ab-2; GM-Tg-cynog-SE1034-Ab-1/ GM-Tg-cynog-SE1034-Ab-2; GM-Tg-felg-SE1034-Ab-1/ GM-Tg-felg-SE1034-Ab-2; GM-Tg-cang-SE1034-Ab-1/ GM-Tg-cang-SE1034-Ab-2; GM-Tg-bovg-SE1034-Ab-1/ GM-Tg-bovg-SE1034-Ab-2; GM-Tg-equg-SE1034-Ab-1/ GM-Tg-equg-SE1034-Ab-2 |
| Products Name | Anti-INSL3 monoclonal antibody |
| Format | mab |
| Target Name | INSL3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-INSL3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1034-Ag-1 | Recombinant multi-species INSL3/ RLF/ RLNL protein |
| ORF Viral Vector | pGMLP003337 | human INSL3 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003337 | human INSL3 Lentivirus particle |
| ORF Viral Vector | pGMLPm004620 | mouse Insl3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004620 | mouse Insl3 Lentivirus particle |
Target information
| Target ID | GM-SE1034 |
| Target Name | INSL3 |
| Gene ID | 3640,16336,114215,100533194,403436,101084860,281870,100146149 |
| Gene Symbol and Synonyms | INSL3,ley-I-L,RLF,RLNL |
| Uniprot Accession | P51460,Q9WUK0,Q6X7V3,O77801 |
| Uniprot Entry Name | INSL3_HUMAN,INSL3_RAT,INSL3_CANLF,INSL3_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000248099 |
| Target Classification | N/A |
The target: INSL3, gene name: INSL3, also named as RLF, RLNL, ley-I-L. This gene encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in this gene may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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