Anti-SFRP5/ SARP3 functional antibody
Anti-SFRP5/ SARP3 functional antibody for cell culture, ELISA & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE1285-Ab-1/ GM-Tg-hg-SE1285-Ab-2 | Anti-Human SFRP5 monoclonal antibody | Human |
GM-Tg-rg-SE1285-Ab-1/ GM-Tg-rg-SE1285-Ab-2 | Anti-Rat SFRP5 monoclonal antibody | Rat |
GM-Tg-mg-SE1285-Ab-1/ GM-Tg-mg-SE1285-Ab-2 | Anti-Mouse SFRP5 monoclonal antibody | Mouse |
GM-Tg-cynog-SE1285-Ab-1/ GM-Tg-cynog-SE1285-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SFRP5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE1285-Ab-1/ GM-Tg-felg-SE1285-Ab-2 | Anti-Feline SFRP5 monoclonal antibody | Feline |
GM-Tg-cang-SE1285-Ab-1/ GM-Tg-cang-SE1285-Ab-2 | Anti-Canine SFRP5 monoclonal antibody | Canine |
GM-Tg-bovg-SE1285-Ab-1/ GM-Tg-bovg-SE1285-Ab-2 | Anti-Bovine SFRP5 monoclonal antibody | Bovine |
GM-Tg-equg-SE1285-Ab-1/ GM-Tg-equg-SE1285-Ab-2 | Anti-Equine SFRP5 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-SE1285-Ab-1/ GM-Tg-hg-SE1285-Ab-2; GM-Tg-rg-SE1285-Ab-1/ GM-Tg-rg-SE1285-Ab-2; GM-Tg-mg-SE1285-Ab-1/ GM-Tg-mg-SE1285-Ab-2; GM-Tg-cynog-SE1285-Ab-1/ GM-Tg-cynog-SE1285-Ab-2; GM-Tg-felg-SE1285-Ab-1/ GM-Tg-felg-SE1285-Ab-2; GM-Tg-cang-SE1285-Ab-1/ GM-Tg-cang-SE1285-Ab-2; GM-Tg-bovg-SE1285-Ab-1/ GM-Tg-bovg-SE1285-Ab-2; GM-Tg-equg-SE1285-Ab-1/ GM-Tg-equg-SE1285-Ab-2 |
Products Name | Anti-SFRP5 monoclonal antibody |
Format | mab |
Target Name | SFRP5 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-SFRP5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-SE1285-Ag-1 | Recombinant multi-species SFRP5/ SARP3 protein |
ORF Viral Vector | vGMLP004521 | human SFRP5 Lentivirus particle |
ORF Viral Vector | pGMLP004521 | human SFRP5 Lentivirus plasmid |
ORF Viral Vector | pGMAAV000278 | house mouse Sfrp5 AAV plasmid |
ORF Viral Vector | pGMLPm002147 | mouse Sfrp5 Lentivirus plasmid |
ORF Viral Vector | vGMAAV000278 | house mouse Sfrp5 AAV particle |
ORF Viral Vector | vGMLPm002147 | mouse Sfrp5 Lentivirus particle |
Target information
Target ID | GM-SE1285 |
Target Name | SFRP5 |
Gene ID | 6425,54612,309377,707738,486826,101088696,282069,100070673 |
Gene Symbol and Synonyms | SARP3,SFRP5 |
Uniprot Accession | Q5T4F7,Q9XSC1 |
Uniprot Entry Name | SFRP5_HUMAN,SFRP5_BOVIN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | |
Disease | Cancer |
Gene Ensembl | ENSG00000120057 |
Target Classification | Tumor-associated antigen (TAA) |
The target: SFRP5, gene name: SFRP5, also named as SARP3. Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.