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Anti-SODE/ SOD3/ EC-SOD functional antibody
Anti-SODE/ SOD3/ EC-SOD functional antibody for cell culture, ELISA & in-vivo assay
Go to SOD3/SOD3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1299-Ab-1/ GM-Tg-hg-SE1299-Ab-2 | Anti-Human SOD3 monoclonal antibody | Human |
| GM-Tg-rg-SE1299-Ab-1/ GM-Tg-rg-SE1299-Ab-2 | Anti-Rat SOD3 monoclonal antibody | Rat |
| GM-Tg-mg-SE1299-Ab-1/ GM-Tg-mg-SE1299-Ab-2 | Anti-Mouse SOD3 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1299-Ab-1/ GM-Tg-cynog-SE1299-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SOD3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1299-Ab-1/ GM-Tg-felg-SE1299-Ab-2 | Anti-Feline SOD3 monoclonal antibody | Feline |
| GM-Tg-cang-SE1299-Ab-1/ GM-Tg-cang-SE1299-Ab-2 | Anti-Canine SOD3 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1299-Ab-1/ GM-Tg-bovg-SE1299-Ab-2 | Anti-Bovine SOD3 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1299-Ab-1/ GM-Tg-equg-SE1299-Ab-2 | Anti-Equine SOD3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1299-Ab-1/ GM-Tg-hg-SE1299-Ab-2; GM-Tg-rg-SE1299-Ab-1/ GM-Tg-rg-SE1299-Ab-2; GM-Tg-mg-SE1299-Ab-1/ GM-Tg-mg-SE1299-Ab-2; GM-Tg-cynog-SE1299-Ab-1/ GM-Tg-cynog-SE1299-Ab-2; GM-Tg-felg-SE1299-Ab-1/ GM-Tg-felg-SE1299-Ab-2; GM-Tg-cang-SE1299-Ab-1/ GM-Tg-cang-SE1299-Ab-2; GM-Tg-bovg-SE1299-Ab-1/ GM-Tg-bovg-SE1299-Ab-2; GM-Tg-equg-SE1299-Ab-1/ GM-Tg-equg-SE1299-Ab-2 |
| Products Name | Anti-SOD3 monoclonal antibody |
| Format | mab |
| Target Name | SOD3 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SOD3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1299-Ag-1 | Recombinant multi-species SODE/ SOD3/ EC-SOD protein |
| ORF Viral Vector | pGMLP003476 | human SOD3 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003476 | human SOD3 Lentivirus particle |
| ORF Viral Vector | pGMLPm001922 | mouse Sod3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001922 | mouse Sod3 Lentivirus particle |
Target information
| Target ID | GM-SE1299 |
| Target Name | SOD3 |
| Gene ID | 6649,20657,25352,715931,488855,111560198,532481,100146988 |
| Gene Symbol and Synonyms | EC-SOD,ECSOD,ECSODPT,SOD3 |
| Uniprot Accession | P08294,Q08420 |
| Uniprot Entry Name | SODE_HUMAN,SODE_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | Ovary Cancer, IgA glomerulonephritis |
| Gene Ensembl | ENSG00000109610 |
| Target Classification | N/A |
The target: SOD3, gene name: SOD3, also named as EC-SOD. This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress. Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM). Homotetramers consisting of the intact protein, or type C subunit, exhibit high affinity for heparin and are anchored to the ECM. Homotetramers consisting of a proteolytically cleaved form of the protein, or type A subunit, exhibit low affinity for heparin and do not interact with the ECM. A mutation in this gene may be associated with increased heart disease risk. [provided by RefSeq, Oct 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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