Anti-XCL1/ ATAC/ LPTN functional antibody

Anti-XCL1/ ATAC/ LPTN functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to XCL1/XCL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-SE1386-Ab-1/ GM-Tg-hg-SE1386-Ab-2Anti-Human XCL1 monoclonal antibodyHuman
GM-Tg-rg-SE1386-Ab-1/ GM-Tg-rg-SE1386-Ab-2Anti-Rat XCL1 monoclonal antibodyRat
GM-Tg-mg-SE1386-Ab-1/ GM-Tg-mg-SE1386-Ab-2Anti-Mouse XCL1 monoclonal antibodyMouse
GM-Tg-cynog-SE1386-Ab-1/ GM-Tg-cynog-SE1386-Ab-2Anti-Cynomolgus/ Rhesus macaque XCL1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-SE1386-Ab-1/ GM-Tg-felg-SE1386-Ab-2Anti-Feline XCL1 monoclonal antibodyFeline
GM-Tg-cang-SE1386-Ab-1/ GM-Tg-cang-SE1386-Ab-2Anti-Canine XCL1 monoclonal antibodyCanine
GM-Tg-bovg-SE1386-Ab-1/ GM-Tg-bovg-SE1386-Ab-2Anti-Bovine XCL1 monoclonal antibodyBovine
GM-Tg-equg-SE1386-Ab-1/ GM-Tg-equg-SE1386-Ab-2Anti-Equine XCL1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-SE1386-Ab-1/ GM-Tg-hg-SE1386-Ab-2; GM-Tg-rg-SE1386-Ab-1/ GM-Tg-rg-SE1386-Ab-2;
GM-Tg-mg-SE1386-Ab-1/ GM-Tg-mg-SE1386-Ab-2; GM-Tg-cynog-SE1386-Ab-1/ GM-Tg-cynog-SE1386-Ab-2;
GM-Tg-felg-SE1386-Ab-1/ GM-Tg-felg-SE1386-Ab-2; GM-Tg-cang-SE1386-Ab-1/ GM-Tg-cang-SE1386-Ab-2;
GM-Tg-bovg-SE1386-Ab-1/ GM-Tg-bovg-SE1386-Ab-2; GM-Tg-equg-SE1386-Ab-1/ GM-Tg-equg-SE1386-Ab-2
Products NameAnti-XCL1 monoclonal antibody
Formatmab
Target NameXCL1
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-XCL1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-SE1386-Ag-1Recombinant multi-species XCL1/ ATAC/ LPTN protein
    CytokineGM-Tg-g-SE1386-Ag-1chemokine (C motif) ligand 1 (XCL1) protein
    ORF Viral VectorvGMLP000163human XCL1 Lentivirus particle
    ORF Viral VectorpGMLP000163human XCL1 Lentivirus plasmid
    ORF Viral VectorpGMLPm000291mouse Xcl1 Lentivirus plasmid
    ORF Viral VectorvGMLPm000291mouse Xcl1 Lentivirus particle


    Target information

    Target IDGM-SE1386
    Target NameXCL1
    Gene ID6375,100057696
    Gene Symbol and SynonymsATAC,LPTN,LTN,SCM-1,SCM-1a,SCM1,SCM1A,SCYC1,XCL1
    Uniprot AccessionP47992
    Uniprot Entry NameXCL1_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryCytokine Target
    DiseaseN/A
    Gene EnsemblENSG00000143184
    Target ClassificationN/A

    The target: XCL1, gene name: XCL1, also named as ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCM1A, SCYC1. This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1. [provided by RefSeq, Sep 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.