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Anti-XCL1/ ATAC/ LPTN functional antibody
Anti-XCL1/ ATAC/ LPTN functional antibody for cell culture, ELISA & in-vivo assay
Go to XCL1/XCL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1386-Ab-1/ GM-Tg-hg-SE1386-Ab-2 | Anti-Human XCL1 monoclonal antibody | Human |
| GM-Tg-rg-SE1386-Ab-1/ GM-Tg-rg-SE1386-Ab-2 | Anti-Rat XCL1 monoclonal antibody | Rat |
| GM-Tg-mg-SE1386-Ab-1/ GM-Tg-mg-SE1386-Ab-2 | Anti-Mouse XCL1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1386-Ab-1/ GM-Tg-cynog-SE1386-Ab-2 | Anti-Cynomolgus/ Rhesus macaque XCL1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1386-Ab-1/ GM-Tg-felg-SE1386-Ab-2 | Anti-Feline XCL1 monoclonal antibody | Feline |
| GM-Tg-cang-SE1386-Ab-1/ GM-Tg-cang-SE1386-Ab-2 | Anti-Canine XCL1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1386-Ab-1/ GM-Tg-bovg-SE1386-Ab-2 | Anti-Bovine XCL1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1386-Ab-1/ GM-Tg-equg-SE1386-Ab-2 | Anti-Equine XCL1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1386-Ab-1/ GM-Tg-hg-SE1386-Ab-2; GM-Tg-rg-SE1386-Ab-1/ GM-Tg-rg-SE1386-Ab-2; GM-Tg-mg-SE1386-Ab-1/ GM-Tg-mg-SE1386-Ab-2; GM-Tg-cynog-SE1386-Ab-1/ GM-Tg-cynog-SE1386-Ab-2; GM-Tg-felg-SE1386-Ab-1/ GM-Tg-felg-SE1386-Ab-2; GM-Tg-cang-SE1386-Ab-1/ GM-Tg-cang-SE1386-Ab-2; GM-Tg-bovg-SE1386-Ab-1/ GM-Tg-bovg-SE1386-Ab-2; GM-Tg-equg-SE1386-Ab-1/ GM-Tg-equg-SE1386-Ab-2 |
| Products Name | Anti-XCL1 monoclonal antibody |
| Format | mab |
| Target Name | XCL1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-XCL1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1386-Ag-1 | Recombinant multi-species XCL1/ ATAC/ LPTN protein |
| Cytokine | GM-Tg-g-SE1386-Ag-1 | chemokine (C motif) ligand 1 (XCL1) protein |
| ORF Viral Vector | vGMLP000163 | human XCL1 Lentivirus particle |
| ORF Viral Vector | pGMLP000163 | human XCL1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000291 | mouse Xcl1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000291 | mouse Xcl1 Lentivirus particle |
Target information
| Target ID | GM-SE1386 |
| Target Name | XCL1 |
| Gene ID | 6375,100057696 |
| Gene Symbol and Synonyms | ATAC,LPTN,LTN,SCM-1,SCM-1a,SCM1,SCM1A,SCYC1,XCL1 |
| Uniprot Accession | P47992 |
| Uniprot Entry Name | XCL1_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000143184 |
| Target Classification | N/A |
The target: XCL1, gene name: XCL1, also named as ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCM1A, SCYC1. This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1. [provided by RefSeq, Sep 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
