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Anti-TIG1/ RARRES1/ LXNL functional antibody
Anti-TIG1/ RARRES1/ LXNL functional antibody for cell culture, ELISA & in-vivo assay
Go to RARRES1/RARRES1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1475-Ab-1/ GM-Tg-hg-SE1475-Ab-2 | Anti-Human RARRES1 monoclonal antibody | Human |
| GM-Tg-rg-SE1475-Ab-1/ GM-Tg-rg-SE1475-Ab-2 | Anti-Rat RARRES1 monoclonal antibody | Rat |
| GM-Tg-mg-SE1475-Ab-1/ GM-Tg-mg-SE1475-Ab-2 | Anti-Mouse RARRES1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1475-Ab-1/ GM-Tg-cynog-SE1475-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RARRES1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1475-Ab-1/ GM-Tg-felg-SE1475-Ab-2 | Anti-Feline RARRES1 monoclonal antibody | Feline |
| GM-Tg-cang-SE1475-Ab-1/ GM-Tg-cang-SE1475-Ab-2 | Anti-Canine RARRES1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1475-Ab-1/ GM-Tg-bovg-SE1475-Ab-2 | Anti-Bovine RARRES1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1475-Ab-1/ GM-Tg-equg-SE1475-Ab-2 | Anti-Equine RARRES1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1475-Ab-1/ GM-Tg-hg-SE1475-Ab-2; GM-Tg-rg-SE1475-Ab-1/ GM-Tg-rg-SE1475-Ab-2; GM-Tg-mg-SE1475-Ab-1/ GM-Tg-mg-SE1475-Ab-2; GM-Tg-cynog-SE1475-Ab-1/ GM-Tg-cynog-SE1475-Ab-2; GM-Tg-felg-SE1475-Ab-1/ GM-Tg-felg-SE1475-Ab-2; GM-Tg-cang-SE1475-Ab-1/ GM-Tg-cang-SE1475-Ab-2; GM-Tg-bovg-SE1475-Ab-1/ GM-Tg-bovg-SE1475-Ab-2; GM-Tg-equg-SE1475-Ab-1/ GM-Tg-equg-SE1475-Ab-2 |
| Products Name | Anti-RARRES1 monoclonal antibody |
| Format | mab |
| Target Name | RARRES1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-RARRES1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1475-Ag-1 | Recombinant multi-species TIG1/ RARRES1/ LXNL protein |
| ORF Viral Vector | pGMLP004777 | human RARRES1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004777 | human RARRES1 Lentivirus particle |
| ORF Viral Vector | pGMLPm000924 | mouse Rarres1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000924 | mouse Rarres1 Lentivirus particle |
Target information
| Target ID | GM-SE1475 |
| Target Name | RARRES1 |
| Gene ID | 5918,109222,310486,703781,612298,101083955,510102 |
| Gene Symbol and Synonyms | 5430417P09Rik,LXNL,PERG-1,RARRES1,TIG1 |
| Uniprot Accession | P49788 |
| Uniprot Entry Name | TIG1_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | Prostate Cancer, Malignant neoplasm of bladder |
| Gene Ensembl | ENSG00000118849 |
| Target Classification | N/A |
The target: RARRES1, gene name: RARRES1, also named as LXNL, PERG-1, TIG1. This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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