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Anti-ROA2/ HNRNPA2B1/ HNRNPA2 functional antibody
Anti-ROA2/ HNRNPA2B1/ HNRNPA2 functional antibody for cell culture, ELISA & in-vivo assay
Go to HNRNPA2B1/HNRNPA2B1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE1481-Ab-1/ GM-Tg-hg-SE1481-Ab-2 | Anti-Human HNRNPA2B1 monoclonal antibody | Human |
| GM-Tg-rg-SE1481-Ab-1/ GM-Tg-rg-SE1481-Ab-2 | Anti-Rat HNRNPA2B1 monoclonal antibody | Rat |
| GM-Tg-mg-SE1481-Ab-1/ GM-Tg-mg-SE1481-Ab-2 | Anti-Mouse HNRNPA2B1 monoclonal antibody | Mouse |
| GM-Tg-cynog-SE1481-Ab-1/ GM-Tg-cynog-SE1481-Ab-2 | Anti-Cynomolgus/ Rhesus macaque HNRNPA2B1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE1481-Ab-1/ GM-Tg-felg-SE1481-Ab-2 | Anti-Feline HNRNPA2B1 monoclonal antibody | Feline |
| GM-Tg-cang-SE1481-Ab-1/ GM-Tg-cang-SE1481-Ab-2 | Anti-Canine HNRNPA2B1 monoclonal antibody | Canine |
| GM-Tg-bovg-SE1481-Ab-1/ GM-Tg-bovg-SE1481-Ab-2 | Anti-Bovine HNRNPA2B1 monoclonal antibody | Bovine |
| GM-Tg-equg-SE1481-Ab-1/ GM-Tg-equg-SE1481-Ab-2 | Anti-Equine HNRNPA2B1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE1481-Ab-1/ GM-Tg-hg-SE1481-Ab-2; GM-Tg-rg-SE1481-Ab-1/ GM-Tg-rg-SE1481-Ab-2; GM-Tg-mg-SE1481-Ab-1/ GM-Tg-mg-SE1481-Ab-2; GM-Tg-cynog-SE1481-Ab-1/ GM-Tg-cynog-SE1481-Ab-2; GM-Tg-felg-SE1481-Ab-1/ GM-Tg-felg-SE1481-Ab-2; GM-Tg-cang-SE1481-Ab-1/ GM-Tg-cang-SE1481-Ab-2; GM-Tg-bovg-SE1481-Ab-1/ GM-Tg-bovg-SE1481-Ab-2; GM-Tg-equg-SE1481-Ab-1/ GM-Tg-equg-SE1481-Ab-2 |
| Products Name | Anti-HNRNPA2B1 monoclonal antibody |
| Format | mab |
| Target Name | HNRNPA2B1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-HNRNPA2B1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE1481-Ag-1 | Recombinant multi-species ROA2/ HNRNPA2B1/ HNRNPA2 protein |
| ORF Viral Vector | pGMLV000301 | human HNRNPA2B1 Lentivirus plasmid |
| ORF Viral Vector | vGMAP000544 | Human HNRNPA2B1 Adenovirus particle |
| ORF Viral Vector | pGMAP000544 | Human HNRNPA2B1 Adenovirus plasmid |
| ORF Viral Vector | vGMLV000301 | human HNRNPA2B1 Lentivirus particle |
Target information
| Target ID | GM-SE1481 |
| Target Name | HNRNPA2B1 |
| Gene ID | 3181,53379,362361,701821,475260,101098942,507564,100068539 |
| Gene Symbol and Synonyms | 9130414A06Rik,hnRNP,hnrnp-A,HNRNPA2,HNRNPA2B1,HNRNPB1,HNRPA2,HNRPA2B1,HNRPB1,IBMPFD2,RNPA2,SNRPB1 |
| Uniprot Accession | P22626,A7VJC2,Q2HJ60 |
| Uniprot Entry Name | ROA2_HUMAN,ROA2_RAT,ROA2_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000122566 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: HNRNPA2B1, gene name: HNRNPA2B1, also named as HNRNPA2, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, IBMPFD2, RNPA2, SNRPB1. This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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