
Pre-made anti-DHFR monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research.
Cat No.: GM-Tg-hg-T17345-Ab
Pre-made anti-DHFR monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-DHFR mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
The target: DHFR, gene name: DHFR, also named as DHFRP1, DYR. Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014].
Order information
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Catalog No. | List Price (In USD) | Discount Price (In USD) | Qty (Quantity) | Sum (In USD) |
---|---|---|---|---|
GM-Tg-hg-T17345-Ab-1-1mg | 5150 | 3090 | ||
GM-Tg-hg-T17345-Ab-1-10mg | Inquiry | Inquiry | ||
GM-Tg-hg-T17345-Ab-1-100mg | Inquiry | Inquiry | GM-Tg-hg-T17345-Ab-2-1mg | 5150 | 3090 |
GM-Tg-hg-T17345-Ab-2-10mg | Inquiry | Inquiry | ||
GM-Tg-hg-T17345-Ab-2-100mg | Inquiry | Inquiry | GM-Tg-hg-T17345-Ab-xmg | Inquiry | Inquiry |
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Catalog No. | GM-Tg-hg-T17345-Ab-1, GM-Tg-hg-T17345-Ab-2 |
Products Name | Anti-DHFR monoclonal antibody |
Format | mab |
Target Name | DHFR |
Gene ID | DHFR |
Gene Name | DHFR |
Gene Alias | DHFRP1, DYR |
Protein Sub-location | Introcelluar Protein |
Category of antibody | Therapeutics Target antibody |
Derivation (species) | Mouse |
Species Reactivity | Human(H) |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-DHFR monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
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